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Epigenetics Facility

The Epigenetics Core Facility provides an array of state-of-the-art epigenetics research resources and services that include:

  • automated single cell isolation and subsequence nucleic acid extraction
  • quantitative gene expression analysis with special expertise in low input amount
  • DNA/chromatin extraction and fragmentation and protein-nucleic acid association (ChIP) from tissue and enriched population
  • next generation sequencing library preparation (RNA-seq and ChIP-seq) and quality control check

The facility also houses a sophisticated flow cytometry cell sorter that is equipped with 4 lasers and capable of detecting up to 11 colors. The sorter allows automated cytofluorimetric analysis and the sterile sorting of specific cell types.

  • Biomark HD ›

    Automated, high-performance PCR system allowing nanoliter reaction volume with exquisite single-cell sensitivity and consistent results
  • Bioruptor Pico Sonication System

    Bioruptor Pico ›

    All-in-one shearing system for DNA, RNA, and chromatin shearing
  • C1 single cell Autoprep System ›

    Automated single-cell preparation for mRNA sequencing, DNA sequencing, epigenetics or miRNA expression
  • EVOS Auto 2.0 ›

    high performance and fast, automated imaging
  • FACSAria Fusion

    FACSAria Fusion ›

    Four lasers (11 colors) advanced cell sorter with bioprotection
  • MassArray System with Epityper DNA Methylation Analysis

    MASSArray System ›

    A non-fluorescent detection platform utilizing mass spectrometry to accurately measure DNA methylation
  • nanodrop one

    Nanodrop One ›

    DNA, RNA, protein quantification with improved accuracy and early contaminant detection
  • pipetmax

    PIPETMAX ›

    Automated liquid handling with qPCR set-up assistance
  • PippinHT

    PippinHT ›

    High throughput size selection for next-generation sequencing
  • QuantStudio 7 Flex Real-time qPCR system

    QuantStudio ›

    Quantitative PCR applications with additional dyes, formats, and automation options
  • qubit 3.0

    Qubit 3.0 Fluorometer ›

    Sensitive nuclei acid quantification for next-generation sequencing
  • RNAscope assay

    RNAscope ›

    Cutting-edge in situ hybridization (ISH) technology to visualize, localize and quantify RNA molecular expression
  • Tapestation 4200 ›

    Gold standard for sample quality control for next-generation sequencing

For more information, please contact:

  • Jia Liu, Ph.D.
    • Director, Epigenetics Facility
    • Director, Rodent Behavioral Analysis Suite
    • Research Associate Professor, Neuroscience Initiative
    Email: jliu1@gc.cuny.edu
    Phone: 212.413.3183