People

Rinat Abzalimov, Ph.D.

The Biomolecular Mass Spectrometry Facility provides analytical services and expertise to CUNY researchers and their industrial partners, and academic research labs outside the University.

Amédée des Georges, Ph.D.

Since his first class on the subject, Des Georges has been fascinated by protein structures and allosteric control. He found electron microscopy to be a compelling tool to study their function and dynamics, and he joined the Linda Amos lab for his Ph.D to learn its techniques. He subsequently joined the Joachim Frank lab to learn the single-particle technique during his postdoctoral studies.

Still excited by its ability to visualize proteins directly, he continues to foray into the study of protein dynamics with cryo-electron microscopy, trying to learn as much as he can on the allosteric modulation of membrane proteins and on the role this plays in cell signaling. He enjoys exploring science with others, as a conversation in the pursuit of knowledge. He believes in fostering these conversations within his group to make science a fun and exciting pursuit.

The des Georges lab studies structural and functional study of the regulation of large macromolecular complexes using cryo-electron microscopy.

Shana Elbaum-Garfinkle, Ph.D.

The Elbaum-Garfinkle Lab studies protein liquid phase separation and neurodegenerative aggregation using a combination of single molecule fluorescence, soft matter material science and C. elegans genetics.

Denize C. Favaro

The Biomolecular Nuclear Magnetic Resonance (NMR) Facility provides instrumentation, analysis, and expertise to researchers within or outside academia.

Eta A. Isiorho, Ph.D.

Eta Isiorho directs the Macromolecular Crystallization Facility, which provides protein and small molecule crystallization services, instrumentation, X-ray data collection at national synchrotron facilities, as well as X-ray crystallographic support to academic and industrial researchers both within and outside the CUNY.

Eta joins the ASRC from Auburn University, where she was both a postdoctoral fellow and the macromolecular staff scientist in the Department of Chemistry and Biochemistry. She received her Ph.D. from The University of Texas at Austin in Biochemistry while being co-supervised by Drs. Adrian Keatinge-Clay and Hung-wen (Ben) Liu. She obtained her B.S. in Biochemistry from Indiana University Bloomington. She is excited to be a part of the SBI at the ASRC where she also provides crystallographic educational tutorials and guest lectures on macromolecular X-ray crystallography.

Research Interests

Using macromolecular X-ray crystallography to understand protein-ligand interactions and unusual biochemical transformations. Exploring and utilizing various crystallization methods on recalcitrant proteins (almost everything can crystallize if you manipulate it enough). Making structural biology, in particular X-ray crystallography, accessible to historically underserved populations.

Bruce Johnson, Ph.D.

The Johnson Lab works at the interface of computation and experiment in developing new techniques for the analysis and use of NMR data from proteins, RNA and metabolomics studies.

Daniel Keedy, Ph.D.

The Keedy Lab combines computation and experiments to reveal alternative protein conformations and explore how they underlie dynamic functions such as catalysis, ligand binding, and allosteric regulation.

Sebastien Poget