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MALDI-TOF MS Imaging Facility

The MALDI-TOF MS Imaging Facility at the CUNY ASRC is the first core facility with MALDI-TOF MS imaging capacity in the New York metropolitan area. The facility provides MALDI Imaging services to research scientists including tissue preparation, matrix coating, MALDI-MS profiling, and imaging/data analysis. MALDI-MS Imaging is a powerful tool for label-free in situ profiling of proteins, lipids, metabolites and small molecules. Both research institutions and industrial enterprises are welcome to utilize our facility.

The MALDI-TOF MS Imaging Facility is jointly overseen by the Structural Biology Initiative and Neuroscience Initiative.

Complete the online application to become a user of this and other ASRC facilities.

Facility Details

All MSI Services require prior consultation with the core for estimated cost and timeline.

Every MSI project is unique – there is no standard method that will work for any sample. The instruments used, sample preparation, data acquisition method, and analysis software will depend on the tissue type and size, the compounds of interest, the spatial resolution needed, and the goals of each experiment. Additional experiments to assist with or complement MSI may be needed, for example, LC-MS analysis and/or microscopy.

Please contact us to inquire about your project.

For more information, please contact:

  • Ye He, Ph.D.
    • Director, Live Imaging and Bioenergetics Facility
    • Co-Director, MALDI-TOF MS Imaging Facility
    • Research Associate Professor, Neuroscience Initiative
    Phone: 212.413.3182
  • Rinat Abzalimov, Ph.D.
    • Director, Mass Spectrometry Facility
    • Co-Director, MALDI-TOF MS Imaging Facility
    • Research Associate Professor, Structural Biology Initiative
    Phone: 212.413.3236