- Director, Mass Spectrometry Facility
- Co-Director, MALDI-TOF MS Imaging Facility
- Research Assistant Professor, Structural Biology Initiative
Rinat Abzalimov, Ph.D. joins the ASRC from the University of Massachusetts at Amherst, where he served as the Assistant Director of the Biochemistry and Molecular Biology Department’s Mass Spectrometry Center. He earned his Ph.D. at the Ufa Research Center of RAS in Russia, while completing his undergraduate studies at Bashkir State University, also in Russia.
About the Biomolecular Mass Spectrometry Facility
The Biomolecular Mass Spectrometry Facility provides analytical services and expertise to CUNY researchers and their industrial partners, and academic research labs outside the University.
Abzalimov’s active research interests are in the area of development of mass spectrometry-based technologies and their applications to problems related to protein’s higher order structure and conformational dynamics, structural disorders, protein interactions with relevant biological partners, stability of biopharmaceuticals. Other research interests include applications of newly emerging field asymmetric and travelling wave ion mobility, and traditional ion mobility spectrometry techniques for fast and comprehensive analysis of highly heterogeneous mixtures of lipids, carbohydrates and peptides.
J. Yin, E. Spillman, E. S. Cheng, J. Short, Y. Chen, J. Lei, M. Gibbs, J. S. Rosenthal, C. Sheng, Y. X. Chen, K. Veerasammy, T. Choetso, R. Abzalimov, B. Wang, C. Han, Y. He, Q. Yuan. Brain-Specific Lipoprotein Receptors Interact with Astrocyte Derived Apolipoprotein and Mediate Neuron-Glia Lipid Shuttling. Nature Communications, 2021, 12 (1), 2408. DOI: https://doi.org/10.1038/s41467-021-22751-7.
K. Veerasammy, Y. X. Chen, S. Sauma, M. Pruvost, D. K. Dansu, T. Choetso, T. Zhong, D. Marechal, P. Casaccia, R. Abzalimov, Y. He. Sample Preparation for Metabolic Profiling Using MALDI Mass Spectrometry Imaging. JoVE, 2020, No. 166, 62008. DOI: https://doi.org/10.3791/62008.
W. Aguilar, O. Zacarias, M. Romaine, G. Proni, A.G. Petrovic, R.R. Abzalimov, M.M. Paz, E. Champeil. Synthesis of Oligonucleotides containing the cis‐Interstrand Crosslink Produced by Mitomycins in their Reaction with DNA.Chem. Eur. J., 2020, 1-20.
I. Dikiy, U. R. Edupuganti, R. R. Abzalimov, P. P. Borbat, M. Srivastava, J. H. Freed, K. H. Gardner. Insights into histidine kinase activation mechanisms from the monomeric blue light sensor. Proc. Natl. Acad. Sci., 2019, EL346. DOI: 10.1073/pnas.1813586116.
B. B. Minsky, R. R. Abzalimov, C. Niu, Y. Zhao, Z. Kirsch, P. L. Dubin, S. N. Savinov, I. A. Kaltashov. Mass spectrometry reveals a multi-faceted role of glycosaminoglycan chains in factor Xa inactivation by antithrombin. Biochemistry, 2018. DOI: 10.1021/acs.biochem.8b00199.
Lampel, Scott A. McPhee, H.-A. Park, G.G. Scott, S. Humagain, D.R. Hekstra, B. Yoo, P.W.J.M. Frederix, T.-D. Li, R.R. Abzalimov, S.G. Greenbaum, T. Tuttle, C. Hu, C.J. Bettinger and R.V. Ulijn, Polymeric Peptide Pigments with Sequence-encoded Properties, Science, 2017, 356, 1064.
Y. Zhao, R.R. Abzalimov, I.A. Kaltashov. Interactions of Intact Unfractionated Heparin with Its Client Proteins Can Be Probed Directly Using Native Electrospray Ionization Mass Spectrometry. Analytical ChemI, 2016, 88, 1711-1718.
O. Fatunmbi, R.R. Abzalimov, S.N. Savinov, A. Gershenson, I.A. Kaltashov. Interactions of Haptoglobin with Monomeric Globin Species: Insights from Molecular Modeling and Native Electrospray Ionization Mass Spectrometry. Biochemistry, 2016, 55, 1918-1928.
C.G. Pappas, R. Shafi, I.R. Sasselli, H. Siccardi, T. Wang, V. Narang, R. Abzalimov, N. Wijerathne and R.V. Ulijn. Dynamic Peptide Libraries for the Discovery of Supramolecular Nanomaterials. Nat. Nanotechnol., 2016.