• The Purpose-Driven Cell

    Researchers find clues to how the PASK protein impacts cell differentiation. Per-Arnt-Sim (PAS) protein domains are found across all kingdoms of life, from prokaryotes to humans. PAS domains are involved in sensing and integrating metabolic and external signals, which helps cells respond to changes in their environment. Despite the ubiquity of PAS domains, how many Read More [...]

  • Spying on a Shape-Shifting Protein

    New crystallography experiments using high pressure and heat to reveal how proteins change shape could advance the development of novel drugs. NEW YORK, January 12, 2024 — Proteins do the heavy lifting of performing biochemical functions in our bodies by binding to metabolites or other proteins to complete tasks. To do this successfully, protein molecules Read More [...]

  • Top Research Stories

    Every year, CUNY ASRC researchers challenge scientific limits and find the most creative ways to expand the world's understanding of the Earth that we inhabit. Here are 10 stories that offer a glimpse at some of the innovative work produced by our researchers. We hope these stories serve as motivation to pursue your goals and Read More [...]

  • Chemists Create Designer Liquid Bio-Droplets

    Based on simple design rules, strings of polypeptides spontaneously form liquid droplets that fluoresce in red and green.  Biological cells play host to hundreds of thousands of proteins that control myriad chemical processes taking place at once. To avoid chaos, these processes need to be tightly regulated so cells can perform life’s essential tasks. And Read More [...]

  • No Laughing Matter: Recycling Helium Amid a Global Shortage

    A recapture system at the CUNY ASRC saves money and an endangered element. A helium recapture system used by Graduate Center scientists since 2021 has saved thousands of dollars by recycling a dwindling natural resource. Supported by a grant from the National Institutes of Health (NIH), the system captures and recycles close to 90% of Read More [...]

  • Structural Biology Newsletter – Fall 2023

    Get the latest news from the Structural Biology Initiative [...]

  • Kevin Gardner Named the 2023 Stein & Moore Award Recipient

    ASRC Structural Biology Initiative director Kevin Gardner has been named the 2023 Stein & Moore Award recipient. The award, which is sponsored by The Protein Society with support from Wiley Journals, honors researchers who have made sustained high impact research contributions in protein science. In addition to his founding director role at the ASRC, Gardner Read More [...]

  • Welcoming the Newest Members of the CUNY ASRC

    Nanoscience Initiative Wasiq Mahmood, undergraduate student Serter Lüleburgaz, postdoctoral researcher Conor Andrews, high school student Yan Rigual-Rosado, undergraduate student Muhtasim Syed, undergraduate student Emmet Shermanm, CUNY ASRC staff member Julianne Villar, undergraduate student María Pérez Ferreiro, short-term scholar Shayan Salehian, Ph.D. rotation student Hema Kuntrapakam, postdoctoral researcher Supreet Kaur, postdoctoral researcher Surya Marjit, master's student Read More [...]

  • Mark Hauber to Lead the Advanced Science Research Center at the CUNY Graduate Center

    New York, NY, July 20,2023 — The City University of New York Graduate Center is pleased to announce the appointment of Mark Hauber as the executive director of its Advanced Science Research Center (CUNY ASRC). Established in 2014, the CUNY ASRC is a world-class STEM research and education institution dedicated to interdisciplinary science that addresses Read More [...]

  • Study Finds Temperature Can Affect How Small Molecules Bind to Therapeutic Targets

    The discovery could help streamline new drug development. More than 90% of clinical drug development efforts fail every year. A key factor driving the failure rate is that researchers currently have an imperfect method for determining early on whether and how small-molecule drug candidates bind to targeted disease-relevant proteins. A study by a multi-institutional team Read More [...]