Structural Basis for Gating and Activation of RyR1. Cell
A. des Georges, O.B. Clarke, R. Zalk, Q. Yuan, K.J. Condon, R.A. Grassucci, W.A. Hendrickson, A.R. Marks, J. Frank. Structural Basis for Gating and Activation of RyR1. Cell. 2016 Sep […]
Counterion interactions in supramolecular self-assembly
S. Belh, A. Manandhar, G. Huffman, K. Ng, A. Chowdhury, M. Patel, N. Yehya, A. des Georges, S. Loverde, D. Eisele. Counterion interactions in supramolecular self-assembly. Abstracts of Papers of […]
Structure of a mammalian ryanodine receptor
R. Zalk, O.B. Clarke, A. des Georges, R.A. Grassucci, S. Reiken, F. Mancia, W.A. Hendrickson, J. Frank, A.R. Marks. Structure of a mammalian ryanodine receptor, Nature 517, n. 7532, 2015: 44-49. […]
Ligand-induced folding of a two-component signaling receiver domain
V. Ocasio, F. Corrêa and K.H. Gardner. Ligand-induced folding of a two-component signaling receiver domain. Biochemistry, 2015, 54, 1353-1363. […]
Coiled-coil coactivators play a structural role mediating interactions in hypoxia inducible factor heterodimerization
Y. Guo, T.H. Scheuermann, C.L. Partch, D.R. Tomchick and K.H. Gardner. Coiled-coil coactivators play a structural role mediating interactions in hypoxia inducible factor heterodimerization. J. Biol. Chem., 2015, 290, 7707-7721. […]
Isoform-selective and stereoselective inhibition of hypoxia inducible factor-2
T.H. Scheuermann, D. Stroud, C. Sleet, L. Bayeh, C. Shokri, H. Wang, C.G. Caldwell, J. Longgood, J.B. MacMillan, R.K. Bruick, K.H. Gardner and U.K. Tambar. Isoform-selective and stereoselective inhibition of […]
Structure of the HIV-1 RNA packaging signal
S.C. Keane, X. Heng, K. Lu, S. Kharytonchyk, V. Ramakrishnan, G. Carter, S. Barton, A. Hosic, A. Florwick, J. Santos, N.C. Bolden, S. McCowin, D.A. Case, B.A. Johnson, M. Salemi, […]
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
des Georges A, Dhote V, Kuhn L, Hellen CU, Pestova TV, Frank J, Hashem Y. Structure of mammalian eIF3 in the context of the 43S preinitiation complex. Nature. 2015 Sep […]
An optogenetic gene expression system with rapid activation and deactivation kinetics
L.B. Motta-Mena, A. Reade, M.J. Mallory, S. Glantz, O.D. Weiner, K.W. Lynch, K.H. Gardner. An optogenetic gene expression system with rapid activation and deactivation kinetics, Nature Chemical Biology, 2014, 10, 196-202. […]
Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation
G. Rivera-Cancel, W.H. Ko, D.R. Tomchick, F. Correa, K.H. Gardner. Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation, Proc. Natl. Acad. Sci., 2014, 111, 17839-17844. […]