Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B.
Mehlman T. S., Biel J. T., Azeem S. M., Nelson E. R., Hossain S., Dunnett L., Paterson N. G., Douangamath A., Talon R., Axford D., Orins H., von Delft F., […]
Virgil Woods
Farihe Tasnim
Simeng Sun
Allen Sun
Kevin Shionarain
Shivani Sharma
Akshay Raju
The temperature-dependent conformational ensemble of SARS-CoV-2 main protease (Mpro).
A Ebrahim*, BT Riley*, D Kumaran, B Andi, MR Fuchs, S McSweeney, DA Keedy (* contributed equally). “The temperature-dependent conformational ensemble of SARS-CoV-2 main protease (Mpro).” Accepted to IUCrJ (2022). Also available as a bioRxiv preprint […]