Keedy Lab

Pushed to extremes: distinct effects of high temperature versus pressure on the structure of STEP.

Guerrero L*, Ebrahim A*, Riley BT, Kim M, Huang Q, Finke AD, Keedy DA (*contributed equally). Pushed to extremes: distinct effects of high temperature versus pressure on the structure of […]

High-resolution double vision of the allosteric phosphatase PTP1B.

Sharma S, Mehlman (Skaist) T, Sagabala RS, Boivin B, Keedy DA. High-resolution double vision of the allosteric phosphatase PTP1B. Acta Cryst F. 2024. 80(Pt 1):1-12. […]

Alexis Lemberikman

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Room-temperature crystallography reveals altered binding of small-molecule fragments to PTP1B.

Mehlman T. S., Biel J. T., Azeem S. M., Nelson E. R., Hossain S., Dunnett L., Paterson N. G., Douangamath A., Talon R., Axford D., Orins H., von Delft F., […]

Farihe Tasnim

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Simeng Sun

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Allen Sun

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Kevin Shionarain

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Akshay Raju

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Lilliana Guerrero

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