Recent Publications

Structural Biology faculty and staff, fall 2018
Structural Biology Initiative Faculty and Staff | Fall 2018

2019

Elbaum-Garfinkle, S. (2019) Matter over mind: Liquid phase separation and neurodegeneration, J. Biol. ChemIn Press

Ceballos, A.*, McDonald, C.J.*, Elbaum-Garfinkle, S. (2018) Methods and Strategies to Quantify Liquid Phase Separation of Disordered Proteins. Methods in Enzymology, 611:31-50. * Contributed equally

Montemiglio LC, Testi C, Ceci P, Falvo E, Pitea M, Savino C, Arcovito A, Peruzzi G, Baiocco P, Mancia F, Boffi A, des Georges A, Vallone B. Cryo-EM structure of the human ferritin-transferrin receptor 1 complex. Nat Commun. 2019 Mar 8;10(1):1121. doi: 10.1038/s41467-019-09098-w. PubMed PMID: 30850661; PubMed Central PMCID: PMC6408514.

DA Keedy. “Journey to the center of the protein: allostery from multitemperature multiconformer X-­ray crystallography.” Acta Cryst D (2019), 75:123-137. PMID: 30821702.

I. Dikiy, U. R. Edupuganti, R. R. Abzalimov, P. P. Borbat, M. Srivastava, J. H. Freed, K. H. Gardner. (2019) Insights into histidine kinase activation mechanisms from the monomeric blue light sensor. EL346. Proc. Natl. Acad. Sci., DOI: 10.1073/pnas.1813586116.

I. Dikiy, L. Clark, K. H. Gardner, D. M. Rosenbaum. (2019) Isotopic labeling of integral membrane proteins for study by solution NMR relaxation methodsMethods Enzymol., 614: 37-65.

2018

L. Clark, I. Dikiy, D. M. Rosenbaum, K. H. Gardner (2018) On the use of Pichia pastoris for isotopic labeling of human GPCRs for NMR studies. J. Biomol. NMR, 71: 203-211.

A. Dashti, D.B. Hail, G. Mashayekhi, P. Schwander, A. des Georges, J. Frank, A. Ourmazd (co-corresponding author) (2018) Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots. bioRxiv: 291922 (pre-print)

S.T. Glantz, E.E. Berlew, Z. Jaber, B.S. Schuster, K. H. Gardner, B.Y. Chow (2018) Directly light-regulated binding of RGS-LOV photoreceptors to anionic membrane phospholipids.  Proc. Natl. Acad. Sci., 115: E7720-E7727

G. Santulli, D. Lewis, A. des Georges, A. R. Marks, J. Frank (2018). Ryanodine receptor structure and function in health and disease. In Membrane Protein Complexes: Structure and Function (pp. 329-352). Springer, Singapore. DOI: 10.1007/978-981-10-7757-9_11

A. Losi, K. H. Gardner, A. Möglich (2018)  Blue-light receptors for optogenetics.  Chem. Rev.  DOI: 10.1021/acs.chemrev.8b00163

A. J. Noble, V. P. Dandey, H. Wei, J. Brasch, J. Chase, P. Acharya, G. Scarpin M. Rapp, E. T. Eg, W. J. Rice, A. Cheng, C. Negro, L. Shapiro, P.D. Kwong, D. Jeruzalmi, A. des Georges, C. Potter, B. Carragher (2018). Routine single particle CryoEM sample and grid characterization by tomographyeLife7, e34257. DOI: 10.7554/eLife.34257

D.A. Keedy*, Z.B. Hill*, J.T. Biel, E. Kang, T.J. Rettenmaier, J. Brandao-Neto, N.M. Pearce, F. von Delft, J.A. Wells, J.S. Fraser (* contributed equally). (2018) An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. eLife. DOI: 10.7554/eLife.36307.

L. Calisti, M.C. Trabuco, A. Boffi, C. Testi, L.C. Montemiglio, A. des Georges, et al. (2018) Engineered ferritin for lanthanide binding. PLoS ONE 13(8): e0201859. DOI: 10.1371/journal.pone.0201859

B. B. Minsky, R. R. Abzalimov, C. Niu, Y. Zhao, Z. Kirsch, P. L. Dubin, S. N. Savinov, I. A. Kaltashov (2018) Mass spectrometry reveals a multi-faceted role of glycosaminoglycan chains in factor Xa inactivation by antithrombinBiochemistry. DOI: 10.1021/acs.biochem.8b00199.

B. Johnson (2018) From Raw Data to Protein Backbone: Chemical Shifts Using NMRFx Processing and NMRViewJ Analysis. Methods in Molecular Biology.  DOI: 10.1007/978-1-4939-7386-6_13