Francesca Vallese, Ph.D.
AI is a viable alternative to high throughput screening: a 318-target study.
Atomwise AIMS Program: Wallach I, …, Keedy DA, …, Smith KS, …, Singh N, …, Hossain S, …, Dzhumaev S, …, Azeem SM, …, Mehlman T, …, Woods VA…, Heifets […]
Automated multiconformer model building for X-ray crystallography and cryo-EM.
Wankowicz SA, Ravikumar A, Sharma S, Riley BT, Raju A, Hogan D, van den Bedem H, Keedy DA, Fraser JS. Automated multiconformer model building for X-ray crystallography and cryo-EM. eLife. […]
Native dynamics and allosteric responses in PTP1B probed by high-resolution HDX-MS.
Woods VA, Abzalimov RR, Keedy DA. Native dynamics and allosteric responses in PTP1B probed by high-resolution HDX-MS. Protein Science. 2024. 33(6):e5024. […]
Epigenetic Marks Uniquely Tune the Material Properties of HP1α Condensates
P. Deshpande, E. Prentice, A. V. Ceballos, P. Casaccia, S. Elbaum-Garfinkle. Epigenetic Marks Uniquely Tune the Material Properties of HP1α Condensates. Biophysical Journal, 2024, S0006349524002820. […]
Pushed to extremes: distinct effects of high temperature versus pressure on the structure of STEP.
Guerrero L*, Ebrahim A*, Riley BT, Kim M, Huang Q, Finke AD, Keedy DA (*contributed equally). Pushed to extremes: distinct effects of high temperature versus pressure on the structure of […]
High-resolution double vision of the allosteric phosphatase PTP1B.
Sharma S, Mehlman (Skaist) T, Sagabala RS, Boivin B, Keedy DA. High-resolution double vision of the allosteric phosphatase PTP1B. Acta Cryst F. 2024. 80(Pt 1):1-12. […]
Signal-regulated unmasking of nuclear localization motif in the PAS domain regulates the nuclear translocation of PASK.
Xiao, M.†, Dhungel, S., Azad, R., Favaro, D.C., Rajesh, R.P., Gardner, K.H., and Kikani, C.K. (2024) Signal-regulated unmasking of nuclear localization motif in the PAS domain regulates the nuclear translocation […]