Subnanometer structure of an enveloped virus fusion complex on viral surface reveals new entry mechanisms.
Marcink TC, Zipursky G, Cheng W, Stearns K, Stenglein S, Golub K, Cohen F, Bovier F, Pfalmer D, Greninger AL, Porotto M, des Georges A, Moscona A. Subnanometer structure of an […]
PH-Tunable Membrane-Active Polymers, NCMNP2a- x, and Their Potential Membrane Protein Applications.
Hoang Trinh, T. K.; Cabezas, A. J.; Joshi, S.; Catalano, C.; Bakkar Siddique, A.; Qiu, W.; Deshmukh, S.; Georges, A. des; Guo, Y. PH-Tunable Membrane-Active Polymers, NCMNP2a- x, and Their […]
Intermediates in SARS-CoV-2 spike–mediated cell entry
Marcink, T.C., Kicmal, T., Armbruster, E., Zhang, Z., Zipursky, G., Golub, K.L., Idris, M., Khao, J., Drew-Bear, J., McGill, G. Gallagher, T., Porotto, M., des Georges A., Moscona, A., 2022. […]
Jack Mechler
Discovery of a Transferrin Receptor 1-Binding Aptamer and Its Application in Cancer Cell Depletion for Adoptive T-Cell Therapy Manufacturing.
E.L. Cheng, I.I. Cardle, N. Kacherovsky, H. Bansia, T. Wang, Y. Zhou, J. Raman, A. Yen, D. Gutierrez, S.J. Salipante, A. des Georges, M.C. Jensen, S.H. Pun, Discovery of a […]
Cryo-EM Structure of Mechanosensitive Channel YnaI Using SMA2000: Challenges and Opportunities
C. Catalano, D. Ben-Hail, W. Qiu, P. Blount, A. des Georges, Y. Guo, Cryo-EM Structure of Mechanosensitive Channel YnaI Using SMA2000: Challenges and Opportunities. Membranes 11 (11), 849 […]
Andres Cabezas
Investigating gating mechanisms of ion channels using temperature-resolved cryoEM
H. Bansia, C. Catalano, Z. Melville, Y. Guo, A.R. Marks, A. des Georges. Investigating gating mechanisms of ion channels using temperature-resolved cryoEM. Microscopy and Microanalysis , Volume 27 , Supplement […]
ENRICH: A fast method to improve the quality of flexible macromolecular reconstructions
Kazemi M, Sorzano COS, Carazo JM, des Georges A, Abrishami V, Vargas J. ENRICH: A fast method to improve the quality of flexible macromolecular reconstructions. Prog Biophys Mol Biol. 2021 […]