Speaker: Dibyendu Das, Ph.D., Indian Institute of Science Education and Research (IISER) Kolkata, West Bengal, India
Title: Designed Negative Feedback from Transiently formed Catalytic Nanostructures
Abstract: Structures in living systems manipulate the high energy ester bonds of chemical fuels to create dissipative assemblies which can access emergent functions such as catalysis. Highly dynamic and complex systems of microtubules undergo substrate driven change of conformation which leads to polymerization.1 Through this talk, I will show our recent results which demonstrate through a simple model system, the realization of a substrate driven dissipative self-assembled state by utilizing the catalytic effects of histidines on the kinetically stable ester bond.2-4 Out of equilibrium state is achieved due to two distinct pathways both catalyzed by histidine, installed in the simple lipid based structure. Further, I will share the latest data on temporal control of function by these artificial transient systems.3
- Pezzato, C.; Prins, L, J Commun. 2015, 6, 7790.
- Afrose, S. P.; Bal, S.; Chatterjee, A.; Das, K; Das, D* Chem. Int. Ed. 2019 58 15783
- Ahmed, S.;, Chatterjee, A.; Das, K; Das, D* Chemical Science 2019 10 7574-7578
- Bal, S.; Das, K; Ahmed, S.;, Das, D* Chem. Int. Ed. 2019 58 244
Bio: Dibyendu Das is Assistant Professor in the Department of Chemical Sciences of Indian Institute of Science Education and Research (IISER) Kolkata, West Bengal, India. He received his MSc degree in Organic Chemistry at the University of Calcutta (India) (2005), PhD in Supramolecular Chemistry at Indian Association for the Cultivation of Science (Thesis 2010) and postdoctoral training at the Emory University. From Jan 2017, he is working in IISER Kolkata. His lab is actively working in the field of systems chemistry and driven self-assembly.
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