Virgil Woods

Publications

Title
Perdikari A, Woods VA, Ebrahim A, Lawler K, Bounds R, Shah DS, Singh NI, Mehlman (Skaist) T, Riley BT, Sharma S, Morris JW, Keogh JM, Henning E, Smith M, Farooqi IS, DA Keedy* (** co-corresponding authors). Structures of human protein tyrosine phosphatase variants reveal targetable allosteric sites. Journal of Biological Chemistry. 2025.
Woods VA, Sharma S, Lemberikman AM, Keedy DA. Orchestrating function: concerted dynamics, allostery, and catalysis in protein tyrosine phosphatases. Current Opinion in Structural Biology. 2025.
Chartier CA, Woods VA, Xu Y, van Vlimmeren AE, Jovanovic M, McDermott AE, Keedy DA, Shah NH. Allosteric regulation of the tyrosine phosphatase PTP1B by a protein-protein interaction. Protein Science. 2025.
Atomwise AIMS Program: Wallach I, …, Keedy DA, …, Smith KS, …, Singh N, …, Hossain S, …, Dzhumaev S, …, Azeem SM, …, Mehlman T, …, Woods VA…, Heifets A (688 total authors). AI is a viable alternative to high throughput screening: a 318-target study. Scientific Reports. 2024. 2;14(1):7526.
Woods VA, Abzalimov RR, Keedy DA. Native dynamics and allosteric responses in PTP1B probed by high-resolution HDX-MS. Protein Science. 2024. 33(6):e5024.