Shivani Sharma

Publications

Title
Perdikari A, Woods VA, Ebrahim A, Lawler K, Bounds R, Shah DS, Singh NI, Mehlman (Skaist) T, Riley BT, Sharma S, Morris JW, Keogh JM, Henning E, Smith M, Farooqi IS, DA Keedy* (** co-corresponding authors). Structures of human protein tyrosine phosphatase variants reveal targetable allosteric sites. Journal of Biological Chemistry. 2025.
Woods VA, Sharma S, Lemberikman AM, Keedy DA. Orchestrating function: concerted dynamics, allostery, and catalysis in protein tyrosine phosphatases. Current Opinion in Structural Biology. 2025.
Raju A, Sharma S, Riley BT, Djuraev S, Tan Y, Kim M, Mahmud T, Keedy DA. Mapping allosteric rewiring in related protein structures from collections of crystallographic multiconformer models. bioRxiv preprint. 2025.
Wankowicz SA, Ravikumar A, Sharma S, Riley BT, Raju A, Hogan D, van den Bedem H, Keedy DA, Fraser JS. Automated multiconformer model building for X-ray crystallography and cryo-EM. eLife. 2024.
Woods VA, Abzalimov RR, Keedy DA. Native dynamics and allosteric responses in PTP1B probed by high-resolution HDX-MS. Protein Science. 2024. 33(6):e5024.
Sharma S, Mehlman (Skaist) T, Sagabala RS, Boivin B, Keedy DA. High-resolution double vision of the allosteric phosphatase PTP1B. Acta Cryst F. 2024. 80(Pt 1):1-12.