Rein V. Ulijn, Ph.D.

Director, Nanoscience Initiative
Director, ASRC Sensor CAT
Director, NanoBioNYC Program
Einstein Professor of Chemistry, Hunter College

Research Interests

Rein Ulijn’s research group is developing bio-inspired nanotechnology. The fundamental research question that drives his work is how the molecular building blocks and processes of life can be repurposed, combined and simplified to produce functional materials with designed properties and functions that cannot be achieved using existing design approaches. The resulting materials can be produced from sustainable sources and are finding wide-ranging applications ranging from energy harvesting, to sustainable plastics, personal care, sensing, biomedicine.

Job History

2014 – present: Director of the Nanoscience Initiative, Advanced Science Research Center, CUNY
2014 – present: Albert Einstein Professor of Chemistry, Hunter College, CUNY
2019 – present: Director of the ASRC Sensor CAT
2022 – present: Director of the NSF Research Training Grant (NRT) Nanoscience Connected to Life

Publications

Showing 1 to 10 of 89 entries

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N. Berisha, A. Farahpour, M. Ramakrishnan, E. Sherman, R. V. Ulijn, D. A. Heller, M. Panagiotakopoulou, V. Athiyarath, M. Coste, Y. Marciano, E. Sherman, Directed discovery of high-loading nanoaggregates enabled by drug-matched oligo-peptide excipients, Chem, 2025
K. Kaygisiz, R. V. Ulijn, Can Molecular Systems Learn?, ChemSystemsChem, 2025, e202400075
Green, C.M., Sementa, D., Mathur,D., Melinger, J.S., Deshpande, P., Elbaum-Garfinkle, S., Medintz, I.L., Ulijn, R.V., Díaz, S.A. (2024). Sequestration within peptide coacervates improves the fluorescence intensity, kinetics, and limits of detection of dye-based DNA biosensors. Communications Chemistry, 7/1 (49).
K. Barriales, S. Khandaker, A. Jain, D. Sementa, M. N. Nair, T. Wang, J. Tang, C. DelRe, and R.V. Ulijn, Aqueous Graphene Dispersion and Biofunctionalization via Enzymatic Oxidation of Tripeptides, Small, 2024.
D. Sementa, D. Dave, R. Fisher, T. Wang, S. Elbaum-Garfinkle, R.V. Ulijn, Sequence-Tunable Phase Behavior and Intrinsic Fluorescence in Dynamically Interacting Peptides, Angew. Chem. Int. Ed., 2023, in press.
J. Son, S. Parveen, D. MacPherson, Y. Marciano, R.H. Huang, R.V. Ulijn, MMP-responsive nanomaterials , Biomaterials Science, 2023, 11, 6457-6479.
Y. Marciano, N. Nayeem, D. Dave, R.V. Ulijn, M. Contel, N-Acetylation of Biodegradable Supramolecular Peptide Nanofilaments Selectively Enhances Their Proteolytic Stability for Targeted Delivery of Gold-Based Anticancer Agents, ACS Biomater. Sci. Eng., 2023, 9, 3379-3389.
S. Kassem, S.A. McPhee, N. Berisha, R.V. Ulijn, Emergence of Cooperative Glucose-Binding Networks in Adaptive Peptide Systems, J. Am. Chem. Soc., 2023
S. Biswas, S. Banerjee, M.A. Shlain, A.A. Bardin, R.V. Ulijn, B.L. Nannenga, A.M. Rappe, A.B. Braunschweig, Photomechanochemical control over stereoselectivity in the [2+ 2] photodimerization of acenaphthylene, Faraday Discussions, 2023, 241, 266-277.
F.K. Sheehan, H. Wang, D. Podbevšek, E. Naranjo, J. Rivera‐Cancel, C. Moran, R.V. Ulijn, X. Chen, Aromatic Zipper Topology Dictates Water‐Responsive Actuation in Phenylalanine‐Based Crystals, Small, 2023, 2207773.

N. Berisha, A. Farahpour, M. Ramakrishnan, E. Sherman, R. V. Ulijn, D. A. Heller, M. Panagiotakopoulou, V. Athiyarath, M. Coste, Y. Marciano, E. Sherman, Directed discovery of high-loading nanoaggregates enabled by drug-matched oligo-peptide excipients, Chem, 2025

K. Kaygisiz, R. V. Ulijn, Can Molecular Systems Learn?, ChemSystemsChem, 2025, e202400075

Green, C.M., Sementa, D., Mathur,D., Melinger, J.S., Deshpande, P., Elbaum-Garfinkle, S., Medintz, I.L., Ulijn, R.V., Díaz, S.A. (2024). Sequestration within peptide coacervates improves the fluorescence intensity, kinetics, and limits of detection of dye-based DNA biosensors. Communications Chemistry, 7/1 (49).

K. Barriales, S. Khandaker, A. Jain, D. Sementa, M. N. Nair, T. Wang, J. Tang, C. DelRe, and R.V. Ulijn, Aqueous Graphene Dispersion and Biofunctionalization via Enzymatic Oxidation of Tripeptides, Small, 2024.

D. Sementa, D. Dave, R. Fisher, T. Wang, S. Elbaum-Garfinkle, R.V. Ulijn, Sequence-Tunable Phase Behavior and Intrinsic Fluorescence in Dynamically Interacting Peptides, Angew. Chem. Int. Ed., 2023, in press.

J. Son, S. Parveen, D. MacPherson, Y. Marciano, R.H. Huang, R.V. Ulijn, MMP-responsive nanomaterials , Biomaterials Science, 2023, 11, 6457-6479.

Y. Marciano, N. Nayeem, D. Dave, R.V. Ulijn, M. Contel, N-Acetylation of Biodegradable Supramolecular Peptide Nanofilaments Selectively Enhances Their Proteolytic Stability for Targeted Delivery of Gold-Based Anticancer Agents, ACS Biomater. Sci. Eng., 2023, 9, 3379-3389.

S. Kassem, S.A. McPhee, N. Berisha, R.V. Ulijn, Emergence of Cooperative Glucose-Binding Networks in Adaptive Peptide Systems, J. Am. Chem. Soc., 2023

S. Biswas, S. Banerjee, M.A. Shlain, A.A. Bardin, R.V. Ulijn, B.L. Nannenga, A.M. Rappe, A.B. Braunschweig, Photomechanochemical control over stereoselectivity in the [2+ 2] photodimerization of acenaphthylene, Faraday Discussions, 2023, 241, 266-277.

F.K. Sheehan, H. Wang, D. Podbevšek, E. Naranjo, J. Rivera‐Cancel, C. Moran, R.V. Ulijn, X. Chen, Aromatic Zipper Topology Dictates Water‐Responsive Actuation in Phenylalanine‐Based Crystals, Small, 2023, 2207773.

Phone Number

212.413.3380

Email

rulijn@gc.cuny.edu

Web Site

http://www.ulijnlab.com