Adam Braunschweig, Ph.D.

  • Professor, Nanoscience Initiative
  • Professor of Chemistry and Biochemistry, Hunter College

The Braunschweig group leverages organic chemistry, supramolecular chemistry, and material science to address pressing medical, environmental, and electronic challenges.

Specific projects involve (1) the development of organic photovoltaics, (2) the preparation of synthetic carbohydrate receptors, and (3) 4D printing.

Research Interests

  1. Organic Electronic Materials and in particular organic photovoltaics
  2. Glycobiology and the development of molecules that target cell-surface glycans
  3. Organic surface chemistry, including methodology and development of instrumentation for 4D organic nanolithography

Job History

  • 2020 – Current: Professor, Nanoscience Initiative, Advanced Science Research Center, NY
  • 2016 – Current: Associate Professor of Chemistry and Biochemistry, Hunter College, NY
  • 2016 – 2020: Associate Professor, Nanoscience Initiative, Advanced Science Research Center, NY
  • 2013 – 2016: Assistant Professor of Chemistry, University of Miami, FL
  • 2010 – 2012: Assistant Professor, Department of Chemistry and The Molecular Design Institute, New York University (NYU), NY
  • 2007 – 2010: NIH NRSA Postdoctoral Research Fellowship in Cancer Nanotechnology, Northwestern University, IL
  • 2006 – 2007: Postdoctoral Researcher, Department of Chemistry, The Hebrew University of Jerusalem, Israel
  • 2001 – 2006: Graduate Student, Department of Chemistry, University of California, Los Angeles (UCLA), CA

Publications

A.R. Cerullo, M. B. McDermott, L. E. Pepi, Z.L. Liu, D. Barry, S. Zhang, X. Yang, X. Chen, P. Azadi, M. Holford, and A. B. Braunschweig. Comparative mucomic analysis of three functionally distinct Cornu aspersum Secretions. Nature Communications, 2023, 14, 5361.

S. Biswas, S. Banerjee, M.A. Shlain, A.A. Bardin, R.V. Ulijn, B.L. Nannenga, A.M. Rappe, A.B. Braunschweig, Photomechanochemical control over stereoselectivity in the [2+ 2] photodimerization of acenaphthylene, Faraday Discussions, 2023, 241, 266-277.

S. Biswas, S. Banerjee, M. Shlain, A. Bardin, B.L. Nannenga, A. Rappe, A.B. Braunschweig, Photomechanochemical control over stereoselectivity in the [2+2] photodimerization of acenaphthylene, Faraday Discussions, 2022, DOI: tbd.

B. Tapia, G. Yagudayeva, M.F. Bravo, K. Thakur, A.B. Braunschweig, M. Marianski, Binding of Synthetic Carbohydrate Receptors to Enveloped Virus Glycans: Insights From Molecular Dynamics Simulations, Carbohydrate Research, 2022, 108574, DOI: 10.1016/j.carres.2022.108574.

M. Lema, I. Nava-Medina, A.R. Cerullo, R. Abdelaziz, S. Jimenez, J. Geldner, M. Abdelhamid, C.-S. Kwan, L. Kharlamb, M. Neary, and A.B. Braunschweig, Scalable Preparation of Synthetic Mucins via Nucelophilic Ring-Opening Polymerization of Glycosylated N-carboxyanhydridesMacromolecules2022, DOI: 10.1021/acs.macromol.1c02477.

D.J. Valles, Y.S. Zholdassov, and A.B. Braunschweig, Evolution and applications of polymer brush hypersurface photolithography, Polym. Chem2021, DOI: 10.1039/D1PY01073E.

M.B. McDermott, A.R. Cerullo, J. Parziale, E. Achrak, S. Sultana, J. Fred, S. Samad, W. Deng, A.B. Braunschweig, and M. Holford, Advancing Discovery of Snail Mucins Function and Application, Front. Bioeng. Biotechnol.2021, DOI: 10.3389/fbioe.2021.734023.

K. Thakur, M.A. Shlain, M. Mateusz, and A.B. Braunschweig, Regiochemical Effects on the Carbohydrate Binding and Selectivity of Flexible Synthetic Carbohydrate Receptors with Indole and Quinoline Heterocyclic Groups, Eur. J. Org. Chem.2021, DOI: 10.1002/ejoc.202100763.

D.J. Valles, Y.S. Zholdassov, J. Korpanty, S. Uddin, Y. Naeem, D.R. Mootoo, N.C. Gianneschi, and A.B. Braunschweig, Glycopolymer Microarrays with Sub-Femtomolar Avidity for Glycan Binding Proteins Prepared by Grafted-To/Grafted-From Photopolymerizations, Angew. Chem. Int. Ed. 2021, DOI: 10.1002/anie.202105729.

A.M. Levine, H. He, G. Bu, P. Ramos, F. Wu, A. Soliman, Js. Serrano, D. Pietraru, C. Chan, J. Batteas, M. Kowalczyk, S.J. Jang, B.L. Nannenga, M.Y. Sfeif, E.H.R. Tsai, and A.B. Braunschweig, Efficient Free Triplet Generation Follows Singlet Fission in Diketopyrrolopyrrole Polymorphs with Goldilocks Coupling, J. Phys. Chem. C2021, DOI: 10.1021/acs.jpcc.1c02737.

Y.S. Zholdassov, D.J. Valles, S. Uddin, J. Korpanty, N.C. Gianneschi, and A.B. Braunschweig, Orthogonal Images Concealed Within a Responsive 6-Dimensional Hypersurface, Advanced Materials2021, DOI: https://doi.org/10.1002/adma.202100803.

C.-S. Kwan, A.R. Cerullo, and A.B. Braunschweig, Design and synthesis of mucin-inspired glycopolymers, ChemPlusChem2020, DOI: 10.1002/cplu.202000637.

M.F. Bravo, M.A. Lema, M. Marianski, and A.B. Braunschweig, Flexible Synthetic Carbohydrate Receptors as Inhibitors of Viral Attachment, Biochemistry2020, DOI: 10.1021/acs.biochem.0c00732.

A. Cerullo, T.Y. Lai, A.B. Braunschweig* et al., Comparative Animal Mucomics: Inspiration for Functional Materials from Ubiquitous and Understudied Biopolymers, ACS Biomat. Sci. Eng.2020, DOI: 10.1021/acsbiomaterials.0c00713.

M.F. Bravo, K. Palanichamy, M. Shlain, F. Schiro, Y. Naeem, M. Marianski and A.B. Braunschweig, Synthesis and Binding of Mannose‐Specific Synthetic Carbohydrate Receptors, Chem. Eur., 2020, DOI: 10.1002/chem.202000481.

S. Biswas, M. Kumar, A.M. Levine, I. Jimenez, R.V. Ulijn, A.B. Braunschweig, Visible-Light Photooxidation in Water by 1O2-Generating Supramolecular HydrogelsChemical Science, 2020, DOI: 10.1039/x0xx00000x.

K. Palanichamy, A. Joshi, T. Mehmetoglu-Gurbuz, M. F. Bravo, M. Shlain, F. Schiro, Y. Naeem, H. Garg, and A.B. Braunschweig, Anti-Zika Activity of a Library of Synthetic Carbohydrate ReceptorsJournal of Medicinal Chemistry2019, DOI: 10.1021/acs.jmedchem.9b00142.

A. Levine, C. Schierl, B. Basel, M. Ahmed, B. Carmago, D. Guldi, A.B. Braunschweig, Singlet Fission in Combinatorial DiketopyrrolopyrroleRylene Supramolecular FilmsThe Journal of Physical Chemistry2019, 123, 1587.

D.J. Valles, Y. Naeem, C. Carbonell, A.M. Wong, D.R. Mootoo, and A.B. Braunschweig, Maskless Photochemical Printing of Multiplexed Glycan Microarrays for High-Throughput Binding StudiesACS Biomaterials Science & Engineering2019, 5, 3131

D. Kroiss, G. Ashkenasy, A.B. Braunschweig, T. Tuttle, and R. Ulijn, Catalyst: Can Systems Chemistry Unravel the Mysteries of the Chemical Origins of Life?Chem2019in press.

A.M. Wong, D.J. Valles, C. Carbonell, C.L. Chambers, A.Y. Rozenfeld, R.W. Aldasooky, and A.B. Braunschweig, Controlled-Height Brush Polymer Patterns via Surface-Initiated Thiol-Methacrylate PhotopolymerizationsACS Macro Lett.2019, 8, 1474.

D.J. Valles, Y. Naeem, A.Y. Rozenfeld, R.W. Aldasooky, A.M. Wong, C. Carbonell, D.R. Mootoo, and A.B. Braunschweig, Multivalent binding of concanavalin A on variable-density mannoside microarraysFaraday Discuss., 2019.

A. Levine, S. Biswas, and A.B. Braunschweig, Photoactive Organic Material Discovery with Combinatorial Supramolecular AssemblyNanoscale Adv., 2019.

Carbonell, D.J. Valles, A.M. Wong, M.W. Tsui, M. Niang and A.B. Braunschweig, Massively Multiplexed Tip-Based Photochemical Lithography under Continuous Capillary FlowCHEM.2018.

Palanichamy, M.F. Bravo, M. Shlain, F. Schiro, Y. Naeem and A.B. Braunschweig, Binding Studies on a Library of InducedFit Carbohydrate Receptors with Mannoside SelectivityChemistry – A European Journal2018.

C. Carbonell and A.B. Braunschweig, Toward 4DNanoprinting with Tip-Induced Organic surface ReactionsAccounts of Chemical Research2017, 50, 190

X. Liu, C. Carbonell and A.B. Braunschweig. 4D Nanolithography Will Require Synergistic Advances in Surface Chemistry, Nanolithography, and Characterization. RSC Chemical Society Reviews2016, DOI: 10.1039/c6cs00349d.

L.M. Smieska, Z. Li, D. Ley, A.B. Braunschweig and J.A. Marohn. Trap-clearing Spectroscopy in Perylene Diimide Derivatives. Chemistry of Materials2016.

X. Liu, Y. Zheng, E. Khothari, S.R. Peurifoy, Y. Ji and A.B. Braunschweig. 4D Polymer Patterning Within a Massively Parallel Flow-Through Photochemical Reactor. Polymer Chemistry20167, 3229 – 3235

Y. Zhou, C.X. Guzman, L.C. Helguero-Kelley, C. Liu, S. Peurifoy, B. Captain and A.B. Braunschweig. Diketopyrrolopyrrole assembly into J-aggregates. Journal of Physical Organic Chemistry2016.

X. Liu, Y. Zheng, S.R. Peurifoy, E. Kothari and A.B. Braunschweig. Optimization of 4D Polymer Printing Within a Massively Parallel Flow-Through Photochemical Microreactor. Polymer Chemistry2016.

Y. Zhu, C.J. Munro, M.J. Olszta, D.J. Edwards, A.B. Braunschweig, M.R. Knecht and N.D. Browning. Dose-Rate Controlled Energy Dispersive X-Ray Spectroscopic Mapping of the Metallic Components in a Biohybrid Nanosystem. Semiconductor Science and Technology2016.

H. Shokri Kojori, H. Ji, Y. Paik, A.B. Braunschweig and S.J. Park. Monitoring Interfacial Lectin Binding With Nanomolar Sensitivity Using a Plasmon Field Effect Transistor. Nanoscale, 2016, 8, 17357 – 17364

X. Liu, C. Carbonell and A.B. Braunschweig. Towards Scanning Probe Lithography-Based 4D Nanoprinting by Advancing Surface Chemistry, Nanopatterning Strategies, and Characterization Protocols. Chemical Society Reviews2016, 45, 6289.

S.R. Peurifoy, C.X. Guzman and A.B. Braunschweig, Topology, assembly, and electronics: three pillars for designing supramolecular polymers with emergent optoelectronic behaviorPolymer Chemistry2015.

C.X. Guzman, R.M. Krick Calderon, Z. Li, S. Yamazaki, S.R. Peurifoy, C. Guo, S.K. Davidowski, M.M.A. Mazza, X. Han, G.P. Holland, A.M. Scott and A.B. Braunschweig, Extended Charge Carrier Lifetimes in Hierarchical Donor-Acceptor Supramolecular Polymer FilmsJournal of Physical Chemistry2015.

S. Rieth, M.R. Miner, C.M. Chang, B. Hurlocker and A.B. Braunschweig, Saccharide Receptor Achieves Concentration Dependent Mannoside Selectivity Through Two Distinct Cooperative Binding PathwaysChemical Science, 2013,4, 357–367.

S. Bian, A.M. Scott, Y. Cao, Y. Liang, S. Osuna, K.N. Houk, and A.B. Braunschweig, Covalently Patterned Graphene Surfaces by a Force Accelerated Diels-Alder Reaction, Journal of the American Chemical Society, 2013, 135, 9240 – 9243

X. Han, S. Bian, Y. Liang, K.N. Houk and A.B. Braunschweig, Reactions in Elastomeric Nanoreactors Reveal the Role of Force on the Kinetics of the Huisgen Reaction on Surfaces, Journal of the American Chemical Society, 2014, 136, 10553–10556

D. Ley, C.X. Guzman, K.H. Adolfsson, A.M. Scott and A.B. Braunschweig, Emergent Charge Transfer in Cooperatively Assembling Donor-Acceptor SuperstructuresJournal of the American Chemical Society, 2014, 136, 7809 – 7812.