We are interested in understanding how this complex network develops and works during health and how its dysfunction leads to disease state. To answer these questions, we are using an array of advanced technologies and tools, while developing interdisciplinary collaborations.
The MRI Facility houses a Siemens 3 Tesla Prisma MRI Scanner equipped with a variety of RF coils: 20, 32, and 64 channel head/neck receivers, total spine RF coil integrated into the table, 3 flex coils for arm, leg, or chest imaging, and a body coil for whole body imaging. A wide range of additional ancillary equipment and related software is also available.
The Epigenetics Core Facilities provide a wide array of state-of-the-art epigenetics research resources and services, including a sophisticated flow cytometry cell sorter that is equipped with 4 lasers and capable of detecting up to 11 colors.
The Rodent Behavioral Analysis Suite contains three high-quality sound-attenuating test rooms, equipped to allow the behavioral assessment of a variety of panels of anxiety, depression, learning tasks, and automated motor function characterization.
The Live Imaging and Bioenergetics Facility houses three core instruments: 1) Zeiss LSM880 upright two photon confocal microscope with Airyscan, FAST model and CLARITY lens, 2) LSM880 inverted live cell imaging confocal microscope with Airyscan and FAST model, and 3) Agilent Seahorse XFe24 live cell metabolic analyzer.
The MALDI-TOF MS Imaging Joint Facility of the Structural Biology Initiative and Neuroscience Initiative at the ASRC at The Graduate Center, CUNY houses four core instruments: 1) Bruker Autoflex Speed TOF, 2) HTX M5 Matrix Sprayer, 3) Leica Aperio CS2 slide scanner, and 4) SCiLS MALDI Imaging Analysis workstation.