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New York City Integrative Structural Biology Symposium

Integrative structural biology is a powerful approach to understand biological macromolecular systems. By combining computational methods with structural science disciplines, spatial and temporal models of macromolecular targets in their in-situ context can be determined. The focus of this symposium is to introduce integrative structural biology to our structural sciences community. The fields of light microscopy, mass spectrometry, X-ray crystallography, NMR, cryo-EM, and computational methods will be highlighted. The topics will cover the best practices and current research toward building structural models across different resolution scales. This symposium will also explore how experimental and computational methods can be integrated to address conformational changes, flexibility, and dynamics in macromolecular structures.

Symposium Agenda

08:30-09:30 Registration Registration & poster setup
09:30-09:35 Opening Welcome
09:35-10:10 Keynote Setting the scene for integrative structural biology

  • Michael Rout (Rockefeller University)
10:10-12:05 Session 1 S4 – Size, shape, stoichiometry, and signals
Techniques: Mass spec / single molecule & fluorescence imaging / AFM

  • Brian Chait (Rockefeller University)
  • Anthony Fitzpatrick (Columbia University)
  • Alisha Jones (New York University)
  • Ruben Gonzalez (Columbia University)
12:05-14:05 Mid-day Session Lunch followed by poster sessions, vendor talks & tours of ASRC and NYSBC.
14:05-15:30 Session 2 Bridging scales from atoms to cells
Techniques: X-ray / NMR / cryo-EM/ET

  • Chris Lima (Memorial Sloan Kettering Cancer Center)
  • Olga Boudker (Weill Cornell Medical College)
  • Alex de Marco (New York Structural Biology Center)
16:15-17:40 Session 3 Computational approaches to combine multi-scale data
Techniques: Modeling / MD / ML&AI

  • Amédée des Georges (City University of New York)
  • Pilar Cossio (Flatiron Institute)
  • Hashim Al-Hashimi (Columbia University)
17:40-17:45 Closing Farewell and poster prizes
17:45 Reception Light snacks & drinks


This symposium is offered at NO COST but is limited to 100 attendees.

Abstract deadline: July 14, 2023.

Application deadline: August 18, 2023.

Speaker bios and further event details can be found here.


We will reach out to abstract applicants by the beginning of August. For further inquiries, please email the organizers at nyc-isb23@nysbc.org.


Sponsored by:


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Event Information

October 13, 2023
9:30 am - 8:00 pm
ASRC Auditorium & Cafe
85 St. Nicholas Terrace
New York, NY 10031 United States
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(212) 413-3300
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