Integrative structural biology is a powerful approach to understand biological macromolecular systems. By combining computational methods with structural science disciplines, spatial and temporal models of macromolecular targets in their in-situ context can be determined. The focus of this symposium is to introduce integrative structural biology to our structural sciences community. The fields of light microscopy, mass spectrometry, X-ray crystallography, NMR, cryo-EM, and computational methods will be highlighted. The topics will cover the best practices and current research toward building structural models across different resolution scales. This symposium will also explore how experimental and computational methods can be integrated to address conformational changes, flexibility, and dynamics in macromolecular structures.
Symposium Agenda
| 08:30-09:30 | Registration | Registration & poster setup |
| 09:30-09:35 | Opening | Welcome |
| 09:35-10:10 | Keynote | Setting the scene for integrative structural biology
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| 10:10-12:05 | Session 1 | S4 – Size, shape, stoichiometry, and signals Techniques: Mass spec / single molecule & fluorescence imaging / AFM
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| 12:05-14:05 | Mid-day Session | Lunch followed by poster sessions, vendor talks & tours of ASRC and NYSBC. |
| 14:05-15:30 | Session 2 | Bridging scales from atoms to cells Techniques: X-ray / NMR / cryo-EM/ET
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| 16:15-17:40 | Session 3 | Computational approaches to combine multi-scale data Techniques: Modeling / MD / ML&AI
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| 17:40-17:45 | Closing | Farewell and poster prizes |
| 17:45 | Reception | Light snacks & drinks |
This symposium is offered at NO COST but is limited to 100 attendees.
Abstract deadline: July 14, 2023.
Application deadline: August 18, 2023.
We will reach out to abstract applicants by the beginning of August. For further inquiries, please email the organizers at nyc-isb23@nysbc.org.
Sponsored by:
