Join the Neuroscience Initiative for their final spring Mini Symposium on Metabolism: Function & Imaging. Please register to attend for both in-person and virtual access, before Wednesday the 25th at noon, here. This event will take place in the ASRC auditorium and a zoom link will be emailed to those who register in advance.
1:00 pm – 1:15 pm Check-in & Coffee
1:15 pm – 1:30 pm Welcome: Dr. Patrizia Casaccia & Dr. Ye He
1:30 pm – 2:30 pm Metabolism Function: Dr. Yuanquan Song
2:30 pm – 3:30 pm Metabolism Imaging: Dr. Wei Min
3:30 pm – 5:00 pm Reception
Yuanquan Song, PhD
Assistant Professor of Pathology and Laboratory Medicine
Perelman School of Medicine, University of Pennsylvania
The Children’s Hospital of Philadelphia
Glial Metabolic Rewiring And Neuronal Intrinsic Reprogramming To Promote Neural Repair
Axons in the mature central nervous system (CNS) fail to regenerate after axotomy, due to the loss of neuronal intrinsic growth potential and the extrinsic inhibitory environment constituted by reactive glial cells. We aim to identify, characterize and manipulate programs in and out of the neurons to achieve axon regrowth and behavioral recovery. Our latest work has revealed glial metabolism and neuronal mechanosensation as critical mediators of axon regeneration, and potential therapeutic targets for treating neural injury.
Wei Min, PhD
Professor of Chemistry
Dept of Chemistry & Dept of Biomedical Engineering
Kavli Institute for Brain Science, Columbia University
Towards Mapping Metabolic Tissue Atlas
Understanding metabolism is of great significance to decipher various physiological and pathogenic processes. While great progress has been made to profile gene expression, how to capture organ-, tissue-, and cell-type-specific metabolic profiles (i.e., metabolic tissue atlas) in mammalian systems is lagging behind. Here we will present a metabolic imaging technology by integrating advances in optical spectroscopy, chemical biology and data science. This allows us to identify spatially-resolved metabolic signatures of brain and tumor, tissue and cell-type specific metabolic profile in situ. Overall, the integrated platform has great potential to map metabolic atlas ranging from cellular scale, tissue-scale, to organ-scale.
For info and questions, please contact Dr. Ye He: firstname.lastname@example.org