Structural Biology: Past, Present and Future
Between ~1950 and ~2010, X-ray crystallography was the experimental technique of choice for determining the structures of biological macromolecules at atomic resolution. It is no longer. Around 2012, following a long gestation, electron microscopy emerged as a serious competitor, and about a decade later, AI-based computational methods were developed that can accurately predict the structure of almost any protein of known sequence. These developments have completely transformed the landscape of the discipline known as structural biology. The speaker will present his view of how the field of structural biology has evolved, and what it has taught us. He will also discuss some of the issues he thinks will need to be addressed if the field is to thrive.
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For any questions, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu.