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ASRC-CCNY Seminar Series in Biochemistry, Biophysics and Biodesign: Pilar Cossio, Flatiron Institute

In this weekly seminar series, Pilar Cossio, Research Scientist and Project Leader for the Structural & Molecular Biophysics Center for Computational Mathematics, Flatiron Institute, New York, NY, will present a one-hour talk titled:

Free energies from cryoEM particles

Abstract   Cryo-electron microscopy (cryo-EM) is an experimental technique that measures single-particle projections of biomolecules. Although single-particle cryo-EM is widely used for 3D reconstruction, it has the potential to provide information about a biomolecule’s conformational variability and provide quantitative measurements of probability distributions. However, cryo-EM images are challenging to analyze due to their low signal-to-noise ratio. To address these issues, we developed mathematical methods to infer free-energy profiles and their uncertainties from cryo-EM raw images.

This seminar will be presented in the ASRC Auditorium and broadcast via Zoom, with snacks and refreshments to start at 11:30am in the cafe.

To join these ongoing events via Zoom, please use the meeting info below:

Meeting ID:  968 3104 2138
Passcode:  ASRC-CDI

For more information about this hybrid eventplease contact:

Hyacinth Camillieri


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Event Information

February 8, 2023
12:00 pm - 1:00 pm
ASRC Auditorium & Cafe
85 St. Nicholas Terrace
New York, NY 10031 United States
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(212) 413-3300
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