Join us for the fall semester ASRC-CCNY Seminar Series in Biochemistry, Biophysics and Biodesign every Wednesday at noon! This week’s speaker, Emeritus Professor in the Dept. of Chemistry and Dept. of Biochemistry & Molecular Biology at the University of Georgia, James Prestegard, will present a talk titled, “NMR in the age of AI; What can it tell us about glycans and glycoproteins?”
Abstract Artificial Intelligence (AI) has had an impact on structural biology, both by providing structures of proteins that allow us to focus more on their functional properties and by providing tools that allow us to analyze data more efficiently. I will present two examples from our NMR investigation of glycans and glycoproteins; one applying new resonance assignment strategies for the sparsely isotope labeled glycoprotein, CEACAM1, and one applying a neural net analysis to ring conformations of a monosaccharide found in heparin. Both provide insight into properties of molecules that impact our health, but they also provide an opportunity to learn about the potential and limitations of some exciting new tools for structural biology.
Download James. H. Prestegard Seminar Flyer
* Dr. Prestegard will be giving this talk in person at the ASRC Main Auditorium. For non-CUNY attendees: advance registration is required; please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu no later than Monday, Nov. 13 for entry to the ASRC.