Key Cellular Mechanism Driving Alzheimer’s Disease
The Neuroscience Initiative is engaged in interdisciplinary programs with other initiatives and other institutions to implement interdisciplinary approaches for the study of environmental influences on brain function and behavior and to develop transformative technologies and advanced platforms aimed at promoting mental health. Follow us on Bluesky @asrcneuroscience.bsky.social
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M. Pruvost, H.-J. Park, C. Habermacher, M. Li, M. C. Angulo, J. Liu, P. Casaccia. The Histone Methyltransferases EHMT1 and EHMT2 Repress the Expression of Genes Related to Excitability and Cell Death in Oligodendrocyte Progenitors. Glia, 2025. DOI: https://doi.org/10.1002/glia.70014.
A. Flury, L. Aljayousi, H.-J. Park, M. Khakpour, J. Mechler, S. Aziz, J. D. McGrath, P. Deme, C. Sandberg, F. González Ibáñez, O. Braniff, T. Ngo, S. Smith, M. Velez, D. M. Ramirez, D. Avnon-Klein, J. W. Murray, J. Liu, M. Parent, S. Mingote, et al. A Neurodegenerative Cellular Stress Response Linked to Dark Microglia and Toxic Lipid Secretion. Neuron, 2025, 113 (4), 554-571.e14. DOI: https://doi.org/10.1016/j.neuron.2024.11.018.
M. Amatruda, D. Marechal, M. Gacias, M. Wentling, S. Turpin‐Nolan, J. Morstein, M. Moniruzzaman, J. C. Brüning, N. J. Haughey, D. H. Trauner, P. Casaccia. Neuroprotective Effect of Neuron‐specific Deletion of the C16 Ceramide Synthetic Enzymes in an Animal Model of Multiple Sclerosis. Glia, 2024, glia.24631. DOI: https://doi.org/10.1002/glia.24631.