Past Publications

2017

Clark, L., Dikiy, I., Chapman, K., Rödström, K.E., Aramini, J., LeVine, M., Khelashvili, G., Rasmussen, S.G.F., Gardner, K.H. and Rosenbaum, D.M. (2017) Ligand modulation of sidechain dynamics in a wild-type human GPCR. eLife.  DOI: 10.7554/eLife.28505

Reade, A., Motta-Mena, L.B., Gardner, K.H., Stanier, D.Y., Weiner, O.D. and Woo, S. (2017) TAEL: A zebrafish-optimized optogenetic gene expression system with fine spatial and temporal control. Development.  DOI:  10.1242/dev.139238

2016

Corrêa, F., Key. J., Kuhlman, B. and Gardner K.H. (2016) Computational repacking of the HIF-2α cavity replaces water-based stabilized core. Structure. DOI: 10.1016/j.str.2016.08.014

Norris, M., Fetler, B., Marchant, J. and Johnson, B.A.. J Biomol NMR (2016). NMRFx Processor: a cross-platform NMR data processing program. doi:10.1007/s10858-016-0049-6

F. Corrêa and K.H. Gardner, K.H.  Basis of mutual domain inhibition in a bacterial signaling switch.  Cell Chemical Biology, (2016)

S.T. Glantz, E.J. Carpenter, M. Melkonian, K.H. Gardner, E.S. Boyden, G.K-S. Wong and B.Y. Chow.  Functional and topological diversity of LOV domain photoreceptors.  Proc. Natl. Acad. Sci. USA, 113: E1442-E1451 (2016).

Fatunmbi O., Abzalimov R.R., Savinov S.N., Gershenson A. and Kaltashov I.A.  Interactions of Haptoglobin with Monomeric Globin Species: Insights from Molecular Modeling and Native Electrospray Ionization Mass SpectrometryBiochemistry 55: 1918-1928. (2016)

2015

S.C. Keane, X. Heng, K. Lu, S. Kharytonchyk, V. Ramakrishnan, G. Carter, S. Barton, A. Hosic, A. Florwick, J. Santos, N.C. Bolden, S. McCowin, D.A. Case, B.A. Johnson, M. Salemi, A.Telesnitsky, M.F. Summers, Structure of the HIV-1 RNA packaging signal, Science, 2015, 348:917-921.

T.H. Scheuermann, D. Stroud, C. Sleet, L. Bayeh, C. Shokri, H. Wang, C.G. Caldwell, J. Longgood, J.B. MacMillan, R.K. Bruick, K.H. Gardner, K.H. and U.K. Tambar.  Isoform-selective and stereoselective inhibition of hypoxia inducible factor-2.  J. Med. Chem., 58: 5930-5941. (2015)

Y.  Guo, T.H. Scheuermann, C.L. Partch, D.R. Tomchick and K.H. Gardner.  Coiled-coil coactivators play a structural role mediating interactions in hypoxia inducible factor heterodimerization.  J. Biol. Chem., 290: 7707-7721. (2015)

V. Ocasio, F. Corrêa and Gardner, K.H.  Ligand-induced folding of a two-component signaling receiver domain.  Biochemistry, 54: 1353-1363.  (2015)

2014

G. Rivera-Cancel, W.H. Ko, D.R. Tomchick, F. Correa, K.H. Gardner, Full-length structure of a monomeric histidine kinase reveals basis for sensory regulation,  Proc. Natl. Acad. Sci., 2014, 111, 17839-17844.

R. Zalk, O.B. Clarke, A. des Georges, R.A. Grassucci, S. Reiken, F. Mancia, W.A. Hendrickson, J. Frank, A.R. Marks,, Structure of a mammalian ryanodine receptor, Nature, 2014, 517, 44–49.

L.B. Motta-Mena, A. Reade, M.J. Mallory, S. Glantz, O.D. Weiner, K.W. Lynch, K.H. Gardner, An optogenetic gene expression system with rapid activation and deactivation kinetics, Nature Chemical Biology, 2014, 10, 196-202.