Xingjian (Jim) Xu

  • Doctoral Student, Gardner Lab, Structural Biology

Xingjian (Jim) Xu obtained his B.Sc. in molecular biophysics with honors in 2016 from the University of British Columbia, BC, Canada, working on molecular dynamics simulations and binding energy calculations of SOD1 dimers in the lab of Dr. Steven Plotkin. Subsequently, Xingjian obtained his M.Sc. in systems biology from the University of Montreal, QC, Canada, specializing in cell signaling, structural biology, and synthetic biology under the supervision of Dr. Matthew Smith and Dr. Mike Tyers.

Outside the lab, Xingjian enjoys playing various musical instruments like piano and ukulele, and also loves sports such as basketball and swimming.

Research Interests

Ligand binding and protein cavity characterizations using NMR and other biophysical tools.


X. Xu et al. Fragile protein folds: Sequence and environmental factors affecting the equilibrium of two interconverting, stably folded protein conformations. Magn. Reson., 2021. DOI:10.5194/mr-2-63-2021

X. Xu et al. Volume and compressibility differences between two stably folded protein conformations revealed by high pressure NMR. Biophys J, 2021. DOI:10.1016/j.bpj.2020.12.034

X. Xu, R. Godoy-Ruiz, K. A. Adipietro, C. Peralta, D. Ben-Hail, K. M. Varney, M. E. Cook et al. Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly. Proceedings of the National Academy of Sciences, 2020, 117, no. 2: 1049-1058.

headshot: xingjian xu

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