- Doctoral Student, Casaccia Lab, Neuroscience Initiative
David Dansu
David is currently a doctoral student in the Biochemistry program at The Graduate Center, CUNY. He received his Bachelor of Science degree from the University of Ghana. He was involved in evaluating the sub-chronic toxicity of Parkia biglobosa seed extract on Sprague-Dawley rats during his undergraduate years at the Center for Plant Medicine Research, Ghana. After graduating with a first-class honors in Biochemistry, Cell and Molecular Biology in 2015, he served as a Teaching Assistant for a year. David got exposed to research in neuroscience during his graduate laboratory rotations and has since been curious to understand the molecular mechanisms of neurodegeneration and myelination. He joined the CUNY Advanced Science Research Center’s Neuroscience Initiative in May 2018.
Research Interests
Dave is currently studying epigenetic control of gene expression during the differentiation of oligodendrocyte progenitor cells (OPCs) into mature oligodendrocytes (mOL) and also during the transition of neonatal OPCs to adult OPCs.
Publications
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D. K. Dansu, J. Liang, I. Selcen, H. Zheng, D. F. Moore, P. Casaccia. PRMT5 Interacting Partners and Substrates in Oligodendrocyte Lineage Cells. Front. Cell. Neurosci., 2022, 16, 820226. DOI: https://doi.org/10.3389/fncel.2022.820226.
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D. Marechal, D. K. Dansu, K. Castro, J. Patzig, L. Magri, B. Inbar, M. Gacias, S. Moyon, P. Casaccia. N-Myc Downstream Regulated Family Member 1 (NDRG1) Is Enriched in Myelinating Oligodendrocytes and Impacts Myelin Degradation in Response to Demyelination. Glia. 2021 Oct 23. DOI: https://doi.org/10.1002/glia.24108. |
K. Veerasammy, Y. X. Chen, S. Sauma, M. Pruvost, D. K. Dansu, T. Choetso, T. Zhong, D. Marechal, P. Casaccia, R. Abzalimov, Y. He. Sample Preparation for Metabolic Profiling Using MALDI Mass Spectrometry Imaging. JoVE, 2020, No. 166, 62008. DOI: https://doi.org/10.3791/62008.
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D. K. Dansu, S. Sauma, P. Casaccia. Oligodendrocyte Progenitors as Environmental Biosensors. Semin Cell Dev Biol, 2020. DOI: https://doi.org/10.1016/j.semcdb.2020.09.012. |
R.G. Lim, O. Al-Dalahmah, J. Wu, M. P. Gold, J. C. Reidling, G. Tang, M. Adam, D. K. Dansu, H.-J. Park, P. Casaccia, R. Miramontes, A. M. Reyes-Ortiz, A. Lau, R. A. Hickman, F. Khan, F. Paryani, A. Tang, K. Ofori, E. Miyoshi, N. Michael, et al. Huntington Disease Oligodendrocyte Maturation Deficits Revealed by Single-Nucleus RNAseq Are Rescued by Thiamine-Biotin Supplementation. Nat Commun, 2022, 13 (1), 7791. DOI: https://doi.org/10.1038/s41467-022-35388-x. |
