Single-Residue Mutation Switch Reconfigures the Hierarchical Structure and Assembly of Amphiphilic Protein Block Copolymers for Hydration Layer-Dominated Water-Responsive Actuation

Jonathan W. Sun, Chengyu Sun, Seungri Kim, Andrew L. Wang, Isabella Huang, Nada Haq-Siddiqi, Zara Hedaya, Raymond S. Tu, Xi Chen*, Jin Kim Montclare*. Single-Residue Mutation Switch Reconfigures the Hierarchical Structure and Assembly of Amphiphilic Protein Block Copolymers for Hydration Layer-Dominated Water-Responsive Actuation. Biochemistry, 65, 2165-2179 (2026).