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Mass Spectrometry Facility

The Mass Spectrometry Facility provides analytical services and expertise in mass spectrometry to CUNY researchers and their industrial partners, academic research labs outside the University. Current services support projects from across structural biology, chemistry, and bio-nanotechnology areas. Examples include characterization of new self-assembling biomaterials, intact proteins, small molecule and complex peptide mixtures, PEGylated biopolymers.

The facility maintains ultra-high resolution maXis-II / ETD ESI-q-TOF, equipped with Dionex Ultimate-3000 U(H)PLC and RS-nano-LC systems, and Autoflex-Speed MALDI TOF-TOF mass-spectrometers. Bruker’s maXis-II/ETD features latest developments in TOF technology to provide confidence for accurate mass measurements and molecular formula determination. Bruker’s Autoflex-Speed hardware options include both linear and high-resolution reflectron modes, LIFTTM technology for structural analysis of peptides. Several orders of magnitude dynamic range of both instruments ensure highly sensitive mass measurements at sufficient speed.

The facility offers training on Autoflex MALDI TOF-TOF for researchers planning to use the equipment extensively.

  • Bruker Autoflex Speed TOF-TOF

    Bruker Autoflex Speed TOF/TOF ›

    Features a number of options, including linear mode, high-resolution reflectron mode, LIFT technology to enable the use of various MS/MS techniques and fully automated plate management for label-free high throughput screening.
  • Bruker Maxis II ETD

    Bruker maXis-II ETD ESI-qTOF ›

    Equipped with Dionex Ultimate-3000 LC system; combines latest hardware innovations in TOF technology with unique software packages that deliver sub-ppm mass accuracy and up to 80,000 mass resolution.

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