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X-ORIGINAL-URL:https://asrc.gc.cuny.edu
X-WR-CALDESC:Events for The Advanced Science Research Center
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DTSTART;VALUE=DATE:20220901
DTEND;VALUE=DATE:20221001
DTSTAMP:20260506T014914
CREATED:20220829T171650Z
LAST-MODIFIED:20230725T195637Z
UID:10001301-1661990400-1664582399@asrc.gc.cuny.edu
SUMMARY:EHOS Training Schedule September 2022
DESCRIPTION:EHOS Training Schedule September 2022 \n  These are Zoom trainings.  The login and Pass Code information are located on the schedule and registration is not required.  \nAfter training\, the instructor will then send you a certificate and our training records will be updated to show that you have completed all requirements before working in the labs etc. \nOf note\, additional trainings on other safety related topics will be coming out in the near future.  We are working with CUNY Central and several other sister CUNY schools to procure a training program that will cover many\, if not all\, of the other topics our researchers need and are required by the regulatory agencies.  These include Biosafety\, IACUC\, Laser Safety\, OSHA safety modules and more\, with further info. to be provided soon. \nBelow you will see trainings that are being offered.  Some of these are required for access to labs at ASRC and some for specialized work being conducted in specific labs.  The newest training being offered is the OSHA Blood-borne Pathogens.  This is a required training.  Almost every lab has some form of sharp object in use (needles\, razors\, pipettes and so on).  From OSHA\, NIH to most other regulatory agencies this training is required. \n\n\n\nTopic\nDate\nTime\nMeeting ID/Pass Code\n\n\nLab Safety\nThursday \n09-01-22\n12:00 PM –1:30 PM\n817 3307 5350/211786\n\n\nC14 FDNY Fire Safety\nTuesday \n09-06-22\n12:00 PM –1:30 PM\n838 4716 4098/654090\n\n\nOSHA Blood-borne Pathogens\nTuesday \n09-13-22\n12:00 PM –1:00 PM\n824 8471 6660/450203\n\n\nCryogenic Safety\nWednesday \n09-14-22\n12:00 PM – 1:00 PM\n868 2028 3534/724043\n\n\nLab Safety\nThursday \n9-15-22\n12:00 PM –1:30 PM\n836 3378 7267/936941\n\n\nC14 FDNY Fire Safety\nTuesday \n09-20-22\n12:00 PM –1:30 PM\n833 7019 1876/004256\n\n\nOSHA Blood-borne Pathogens\nThursday \n09-22-22\n12:00 PM –1:00 PM\n863 1314 3941/157993\n\n\nCryogenic Safety\nTuesday \n09-27-22\n12:00 PM  – 1:00 PM\n864 4427 2147/663857\n\n\nLab Safety\nWednesday \n09-28-22\n12:00 PM – 1:30 PM\n893 2082 4922/323374\n\n\nOSHA Blood-borne Pathogens\nThursday \n9-29-22\n12:00 – 1:00 PM\n872 4406 6977/676241\n\n\n\n  \nFor questions\, please contact: \nThomas Dickson \nEnvironmental Health and Occupational Safety \nASRC – Graduate Center CUNY \n85 St.Nicholas Terrace \nNew York\, NY 10031 \nP: (212)-413-3351 \nM: (917)-414-4608 \nE: tdickson@gc.cuny.edu \n 
URL:https://asrc.gc.cuny.edu/event/ehos-training-schedule-september-2022/
LOCATION:Online
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220907T120000
DTEND;TZID=America/New_York:20220907T130000
DTSTAMP:20260506T014914
CREATED:20220627T163437Z
LAST-MODIFIED:20220817T162210Z
UID:10001137-1662552000-1662555600@asrc.gc.cuny.edu
SUMMARY:ASRC-CCNY Seminar Series in Biochemistry\, Biophysics and Biodesign: Paul Lombroso\, Yale University
DESCRIPTION:Please join us for the first talk in this fall seminar series\, to be presented by Paul Lombroso\, Director of the Laboratory of Molecular Neurobiology at Yale University School of Medicine\, New Haven\, CT\, titled: \nTaking STEPs to Improve Cognition \nABSTRACT- The Lombroso laboratory focuses on mammalian learning and how these processes are disrupted in various neuropsychiatric disorders. Central to this investigation is a brain-specific protein tyrosine phosphatase called STEP and its role in regulating intracellular signaling. STEP protein levels are increased in several neuropsychiatric disorders\, including Alzheimer’s disease\, schizophrenia and fragile X syndrome. Earlier work showed that STEP regulates ERK1/2 and Fyn by dephosphorylating and inactivating them. STEP also regulates the cell surface expression of AMPA and NMDA glutamate receptors and leads to their endocytosis. Signals that lead to STEP inactivation potentiate learning\, whereas signals that lead to STEP activation oppose the development of synaptic plasticity. We use biochemical\, molecular\, immunocytochemical\, and behavioral techniques in animal models to address the role that STEP normally plays in regulating aspects of learning and the role STEP plays in cognitive disorders. \nThis seminar will be presented in the ASRC Auditorium and broadcast via Zoom\, with snacks and refreshments to begin at 11:30am. \nTo join these ongoing events via Zoom\, please use the link below: \nZoom access>>> \nFor more information about this hybrid event please contact: \nJennifer Chow \njchow@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-and-biodesign-paul-lambroso-yale-university/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220914T120000
DTEND;TZID=America/New_York:20220914T130000
DTSTAMP:20260506T014914
CREATED:20220627T164748Z
LAST-MODIFIED:20220830T174625Z
UID:10001139-1663156800-1663160400@asrc.gc.cuny.edu
SUMMARY:ASRC-CCNY Seminar Series in Biochemistry\, Biophysics and Biodesign: Amedee des Georges\, ASRC/GC\, CUNY
DESCRIPTION:In this weekly seminar series\, Amedee des Georges\, Assistant Professor at the Advanced Science Research Center at the Graduate Center\, CUNY\, New York\, NY will be giving a one-hour talk titled: \nBio and abstract to come>>> \nThis seminar will be presented in the ASRC Auditorium and broadcasted via Zoom\, with snacks and refreshments to begin at 11:30am. \nTo join these ongoing events via Zoom\, please use the link below: \nZoom access to come>>> \nFor more information about this hybrid event please contact: \nJennifer Chow \njchow@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-and-biodesign-amedee-de-georges-asrc-gc-cuny/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220916T093000
DTEND;TZID=America/New_York:20220916T170000
DTSTAMP:20260506T014914
CREATED:20220816T172813Z
LAST-MODIFIED:20220913T142616Z
UID:10001297-1663320600-1663347600@asrc.gc.cuny.edu
SUMMARY:Are We Ready? NYC Resilience and Sustainability a Decade After Superstorm Sandy
DESCRIPTION:The CUNY ASRC will host a day-long press briefing exploring what the greater New York City area has learned\, where we are\, and where we need to be 10 years after Superstorm Sandy. The far-reaching weather event was a harbinger of a potentially devastating future under climate change\, and a mandate for the greater New York City area to move toward resilience and sustainability so that communities can slow the pace of and withstand climate change. \nThe press event will feature: \n\n3 panels that explore local climate change stressors\, their impact on the lives of NYC residents and communities\, and how the city is faring in addressing the challenge of climate change\nResearch data from CUNY climate change researchers who are working in various capacities across the greater NYC area to address a variety of related issues\nAn update on the NYC Floodnet project and a new local initiative to address climate change\n\nView Agenda \nREGISTER TO ATTEND
URL:https://asrc.gc.cuny.edu/event/are-we-ready-nyc-resilience-and-sustainability-a-decade-after-superstorm-sandy/
LOCATION:Advanced Science Research Center (ASRC)\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220921T120000
DTEND;TZID=America/New_York:20220921T130000
DTSTAMP:20260506T014914
CREATED:20220627T170052Z
LAST-MODIFIED:20220919T190647Z
UID:10001141-1663761600-1663765200@asrc.gc.cuny.edu
SUMMARY:ASRC-CCNY Seminar Series in Biochemistry\, Biophysics and Biodesign: Qing R. Fan\, Columbia University
DESCRIPTION:In this weekly seminar series\, Qing R. Fan\, Associate Professor of Pharmacology\, Pathology\, and Cell Biology at the Columbia University Irving Medical Center\, NY\, will be giving a one-hour talk titled: \n Structural mechanisms of ligand activation in dimeric GPCRs \nABSTRACT Our research seeks to uncover the molecular mechanisms of activation and modulation of dimeric G protein-coupled receptors (GPCRs). GPCRs are distinguished by their seven-helix transmembrane domain which couples with specific G proteins to initiate downstream signaling cascades. They respond to a diverse array of external stimuli and constitute 30-50% of clinical drug targets. \nGPCRs are divided into several classes. The class C family of GPCRs are unique in that they are obligate dimers and possess substantial extracellular domains. These receptors bind activating ligands remotely in the extracellular domain\, which then transmits signals into and through the transmembrane domain for G protein activation. We are working to understand the activation mechanisms in two class C GPCR systems: human GABAB receptor and human calcium-sensing (CaS) receptor. \nGABAB receptor functions as an obligatory heterodimer to mediate inhibitory neurotransmission. We determined the extracellular-domain structures of GABAB receptor in three functional states: in the apo form\, bound to six different antagonists\, and bound to two different agonists. Our structures revealed the molecular mechanisms of ligand recognition and activation in GABAB receptor. \nWe recently solved a structure of near full-length GABAB receptor\, captured in the inactive state by cryo-electron microscopy. Our structure revealed a novel heterodimer interface between the transmembrane domains of GABAB subunits. This interface embodies the signature of GABAB receptor’s inactive conformation. Furthermore\, we identified a unique- intersubunit latch- motif within this transmembrane interface that maintains the inactive state of the receptor\, since its disruption through mutations results in constitutive receptor activity. We also discovered multiple ligands pre-associated with the receptor\, including a Ca2+ near the orthosteric agonist-binding site to upregulate receptor activity and two large endogenous phospholipids embedded within the TM domains to maintain receptor integrity. \nCaS receptor functions as a homodimer to control extracellular Ca2+ homeostasis. We determined the extracellular-domain structures of human CaS receptor in the resting and active conformations. Our structures revealed novel binding sites for Ca2+\, PO43-\, and L-amino acids. Surprisingly\, we discovered that L-amino acids are orthosteric agonists of CaS receptor\, and act jointly with Ca2+ to trigger receptor activation. Additionally\, PO43- mediates inhibition of CaS receptor activity. \nWe recently obtained the structures of a near-full length CaS receptor in three functional states\, an inactive-state structure in the presence of a negative allosteric modulator\, and two active-state structures in the absence and presence of a positive allosteric modulator. We found that CaS receptor activation involves a rearrangement of the transmembrane homodimer and formation of a novel dimer interface. In the inactive structure\, direct transmembrane contact is absent. The critical development during receptor activation arises from a helix-breaking event that facilitates the formation of a transmembrane homodimer interface. \nThis seminar will be presented in the auditorium and via Zoom. \nTo join these ongoing events via Zoom\, please use the link below: \nZoom access >>> \nFor more information about this hybrid event please contact: \nJennifer Chow \njchow@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-and-biodesign-qing-r-fan-columbia-university/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220921T160000
DTEND;TZID=America/New_York:20220921T190000
DTSTAMP:20260506T014914
CREATED:20220707T203813Z
LAST-MODIFIED:20220824T145114Z
UID:10001291-1663776000-1663786800@asrc.gc.cuny.edu
SUMMARY:The 7th Annual Sharon Cosloy - Edward Blank Family Distinguished Scientist Lecture
DESCRIPTION:Please join the CCNY Division of Science for The 7th Annual Sharon Cosloy – Edward Blank Family Distinguished Scientist Lecture with Dr. Titia de Lange on September 21st at 4pm. \nDr. Titia de Lange will be presenting a talk titled: “Telomere shortening: why and how?” \nAbout Dr. Sharon Cosloy: \nDr. Sharon Cosloy was a member of the City College Biology faculty for 27 years and served as Chair of the Biology Department for six years. She was a beloved mentor\, educator\, wife and mother and a passionate investigator of life and science. The Professor Sharon Cosloy and Edward Blank Family Distinguished Scientist Lectureship is regarded as the preeminent scientific lecture on campus. The City College of New York is grateful to Edward Blank and his family for their generous support. \nThis event will take place in the ASRC Auditorium and be broadcast via Zoom\, with refreshments and networking in the adjoining café to follow. An RSVP will be required to join for food/ refreshments and the lecture. \nTo Register>>> \n Zoom access>>> \nMeeting ID: 864 8738 2303\nPasscode: 627130 \nFor further questions\, please contact: \nJason Redman \njredman@ccny.cuny.edu
URL:https://asrc.gc.cuny.edu/event/2022-cosloy-blank-lecture-series/
LOCATION:ASRC Auditorium & Cafe\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220928T120000
DTEND;TZID=America/New_York:20220928T130000
DTSTAMP:20260506T014914
CREATED:20220627T185223Z
LAST-MODIFIED:20220919T190846Z
UID:10001143-1664366400-1664370000@asrc.gc.cuny.edu
SUMMARY:ASRC-CCNY Seminar Series in Biochemistry\, Biophysics and Biodesign: Alexey Silakov\, Pennsylvania State University
DESCRIPTION:In this weekly seminar series\, Alexey Silakov\, Assistant Professor in the Department of Chemistry at Pennsylvania State University\, University Park\, PA\, will be giving a one-hour talk titled: \nBio and abstract to come>>> \nThis seminar will be presented in the ASRC Auditorium and broadcast via Zoom\, with snacks and refreshments to start at 11:30am. \nTo join these ongoing events via Zoom\, please use the link below: \nZoom access >>> \nFor more information about this hybrid event please contact: \nJennifer Chow \njchow@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-and-biodesign-alexey-silakov-pennsylvania-state-university/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220930T140000
DTEND;TZID=America/New_York:20220930T150000
DTSTAMP:20260506T014914
CREATED:20220906T144513Z
LAST-MODIFIED:20220906T145308Z
UID:10001303-1664546400-1664550000@asrc.gc.cuny.edu
SUMMARY:Meet the Librarian: An Introduction to The Graduate Center Library’s Science Resources
DESCRIPTION:Join us on September 30\, 2022\, at 2 p.m. for a session with the CUNY Graduate Center’s Science Librarian Mason Brown\, who will be discussing how to access and discover STEM research materials from off campus. \nConducting science research remotely can be done successfully with a few simple but critical tools. In this session\, Mason will be discussing how to find individual articles\, browse entire journals\, and access other relevant research materials remotely. In addition\, Mason will: \n\n Provide an overview of Zotero citation management software\n•    Highlight useful and notable science-specific databases\n•    Cover journals that can be accessed remotely\n•    Demonstrate how to log-in to resources from home\n\nThere will be opportunity for Q&A. \nYou can sign-up for this month’s Communicating Your Science event at https://bit.ly/3x0EiSW \nFor more information\, contact Josephine Peterson at jpeterson@gc.cuny.edu.
URL:https://asrc.gc.cuny.edu/event/meet-the-librarian-an-introduction-to-the-graduate-center-librarys-science-resources-2/
LOCATION:Advanced Science Research Center (ASRC)\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
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