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X-WR-CALNAME:The Advanced Science Research Center
X-ORIGINAL-URL:https://asrc.gc.cuny.edu
X-WR-CALDESC:Events for The Advanced Science Research Center
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DTSTART;TZID=America/New_York:20211201T120000
DTEND;TZID=America/New_York:20211201T130000
DTSTAMP:20260511T040438
CREATED:20210901T200814Z
LAST-MODIFIED:20211118T183928Z
UID:10001224-1638360000-1638363600@asrc.gc.cuny.edu
SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Neel H. Shah\, Columbia University
DESCRIPTION:Speaker: Neel H. Shah\, Assistant Professor\, Department of Chemistry\, Columbia University \nTitle: Sequence-dependent tuning of inputs and outputs in phosphotyrosine signaling \nAbstract: Signal transduction through protein tyrosine phosphorylation is critical for many core functions of animal cells\, including proliferation\, survival\, programmed death\, and cell-cell communication. These processes are mediated by two large enzyme families\, tyrosine kinases and tyrosine phosphatases\, that collectively control the phosphorylation states of thousands of sites in human proteins. While it is well-established that tyrosine kinases and phosphatases can engage phosphorylation sites in a sequence dependent manner\, we know surprisingly little about how the sequences of phosphosites actually shape and tune signaling pathways. In this talk\, I will describe a high-throughput biochemical platform that we have developed to profile the sequence specificities of phosphotyrosine signaling proteins. I will discuss how this technique has yielded new insights into T cell activation and how it can be used for the large-scale characterization of disease-associated mutations proximal to tyrosine phosphorylation sites. Finally\, I will describe our efforts to understand the sequence-dependent activation of signaling enzymes bearing phosphotyrosine-recognition domains. \nDownload flyer \nParticipate via Zoom » \nFor more information about this seminar\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-neel-h-shah-columbia-university/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211203T140000
DTEND;TZID=America/New_York:20211203T150000
DTSTAMP:20260511T040438
CREATED:20210811T201758Z
LAST-MODIFIED:20211118T214740Z
UID:10001202-1638540000-1638543600@asrc.gc.cuny.edu
SUMMARY:Sharing Your Research Through Images & Graphics
DESCRIPTION:This event is part of the Communicating Your Science series. \nThis series features presentations by The Graduate Center’s science librarian and communications staff\, journal editors\, and reporters. The goal of this series is to enhance the professional development and science communication skills of CUNY STEM faculty\, postdocs\, and students. Learn more » \n\nFrom journal publications to news stories and social media shares\, powerful images are essential to engaging and helping audiences understand new science. \nJoin us for an exciting edition of Communicating Your Science where our expert panel will explore tips and tools for creating graphics and other visuals that convey your research findings to diverse audiences in clear and compelling ways. Hear from: \n\nEd Bell\, a STEM graphic artist and animator\, and the former art director for Scientific American.\nSara Fresard\, a PhD student with the CUNY Graduate Center Biology program and a currentLennihan Arts & Science grantee who is researching how art-based practices can humanize science.\nFloor Grootenhuis\, an artist-in-residence at the Raper Lab at Hunter College where she works with researchers to help them translate their science into a visual language.\n\nThere will be time for Q&A. \nYou can sign-up here for this month’s Communicating Your Science event. \nFor more information\, contact Shawn Rhea at srhea@gc.cuny.edu.
URL:https://asrc.gc.cuny.edu/event/sharing-your-research-through-images-and-graphics/
LOCATION:Online
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211208T120000
DTEND;TZID=America/New_York:20211208T130000
DTSTAMP:20260511T040438
CREATED:20210901T201103Z
LAST-MODIFIED:20211118T185132Z
UID:10001226-1638964800-1638968400@asrc.gc.cuny.edu
SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Samuel Sternberg\, Columbia University Medical Ctr
DESCRIPTION:Speaker: Samuel Sternberg\, Assistant Professor\, Dept of Biochem. & Molecular Biophysics\, Columbia University\nMedical Ctr \nTitle: Evolutionary and mechanistic diversity of CRISPR RNA-guided transposases \nAbstract: Conventional CRISPR–Cas systems maintain genomic integrity by leveraging guide RNAs for the nuclease-dependent degradation of mobile genetic elements\, including plasmids and viruses. In a remarkable inversion of this paradigm\, bacterial transposons have coopted nuclease-deficient CRISPR–Cas systems to catalyze RNA-guided integration of mobile genetic elements into the genome. Here we show that programmable transposition occurs at a fixed distance downstream of target DNA sequences\, accommodates variable length genetic payloads\, and functions robustly in diverse bacterial species. Deep sequencing experiments reveal highly specific\, genome-wide DNA integration\, which is enabled by the coordinated and sequential recruitment of transposase factors to target sites specified by Cascade. By exploring a large set of evolutionarily diverse CRISPR-transposon systems\, we further define key sequence motifs that establish transposase-transposon specificity during DNA excision and integration. The discovery of a fully programmable\, RNA-guided transposase lays the foundation for kilobase-scale genome engineering that obviates the requirements for DNA double-strand breaks and homologous recombination. \nDownload flyer \nParticipate via Zoom » \nFor more information about this seminar\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-samuel-sternberg-columbia-university-medical-ctr/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211209T160000
DTEND;TZID=America/New_York:20211209T180000
DTSTAMP:20260511T040438
CREATED:20211202T160231Z
LAST-MODIFIED:20211202T160231Z
UID:10001100-1639065600-1639072800@asrc.gc.cuny.edu
SUMMARY:CUNY Women in STEM: Building Our Network
DESCRIPTION:Join us for a professional development and networking event open to all CUNY graduate students\, postdoctoral fellows\, and faculty interested in furthering their STEM academic research careers!\nThursday\, December 9\, 2021\n4:00 pm to 6:00 pm \nTen CUNY faculty members and administrative leaders will talk about gender equity and inclusion in STEM\, with an emphasis on academia\, and give advice and tips on how to thrive and succeed. The audience will also have the opportunity to meet colleagues from across CUNY’s campuses during breakout sessions. \nThe event’s participants include:​​​​ \n\nPatrizia Casaccia\, M.D.\, Ph.D.\, Einstein Professor and Initiative Director\, Advanced Science Research Center\, The Graduate Center\nSaavik Ford\, Ph.D.\, Professor\, Borough of Manhattan Community College\nNina Gray\, Ph.D.\, Executive Director and Associate Dean\, Advanced Science Research Center\, The Graduate Center\nMandë Holford\, Ph.D.\, Associate Professor\, Hunter College\nDelaram Kahrobaei\, Ph.D.\, University Dean for Research\nKendra Krueger\, M.S.\, STEM Education and Outreach Manager\, Advanced Science Research Center\, The Graduate Center\nTamera Schneider\, Ph.D.\, Associate Vice Chancellor for Research\nChristina Sormani\, Ph.D.\, Professor\, Lehman College\nYingli Tian\, Ph.D.\, Distinguished Professor\, City College of New York\nRosemarie Wesson\, Ph.D.\, P.E.\, Interim Associate Provost for Research\, City College of New York\n\nPlease register here for the virtual event by December 8. \nOrganized by the CUNY Office of Research.
URL:https://asrc.gc.cuny.edu/event/cuny-women-in-stem-building-our-network/
LOCATION:Online
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
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