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X-WR-CALDESC:Events for The Advanced Science Research Center
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DTSTART;TZID=America/New_York:20211006T120000
DTEND;TZID=America/New_York:20211006T130000
DTSTAMP:20260524T064856
CREATED:20210901T181313Z
LAST-MODIFIED:20211001T181308Z
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SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Yuan He\, Northwestern University
DESCRIPTION:Speaker: Yuan He\, Assistant Professor\, Department of Molecular Biosciences\, Northwestern University \nTitle: Structural Visualization of Chromatin Regulatory Complexes using Cryo-EM \nAbstract: My research program seeks to address the fundamental biological questions of how information stored in DNA is correctly transcribed and how genome integrity is maintained. Transcription is\nthe first process involved in the genetic readout and incorrect spatial and/or temporal patterns of gene transcription contribute to the etiology of many human diseases. The genome is relentlessly subjected to a\nvariety of environmental insults to which cells respond by deploying multiple\, distinct mechanisms to counter the deleterious effects depending on the type of damage sustained. My research program\nintegrates a combination of approaches including protein biochemistry\, biophysics\, and structural biology to elucidate structure-function relationships of complex macromolecular machines. Since establishing\nmy independent laboratory in 2015 at Northwestern University\, we has made significant progress and impactful discoveries addressing fundamental questions regarding how cells have evolved molecular\nmechanisms to read and repair our genome. These include: 1) How does a transcription initiation complex assemble at gene promoters? 2) How does a chromatin remodeling complex expose DNA sequences\nshielded by chromatin? 3) How are DNA double strand breaks (DSBs) detected and repaired? Our work has provided fundamental mechanistic insights into each of these processes at atomic resolution and raised\nimportant questions for future investigations. We anticipate that our scientific contributions have and will continue to shape and advance the exciting\, rapidly growing fields of gene regulation and DNA repair\nwith the results of these studies being directly relevant to human health and disease. \nParticipate via Zoom \nDownload event flyer \nFor more information about this seminar and about joining in online\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-yuan-he-northwestern-univ/
LOCATION:Online
CATEGORIES:Structural Biology
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211008T100000
DTEND;TZID=America/New_York:20211008T140000
DTSTAMP:20260524T064856
CREATED:20210930T141545Z
LAST-MODIFIED:20210930T141545Z
UID:10001092-1633687200-1633701600@asrc.gc.cuny.edu
SUMMARY:Nanoscience Approaches to Cancer
DESCRIPTION:Please register online here. \nBiomaterials at the Interface of Tissue Engineering & Cancer Immunology\nMatthew T. Wolf\, Ph.D.\nLaboratory of Cancer Immunometabolism\, National Cancer Institute \nDNA-Based Nanostructures for Chemical and Biological Analysis\nDevleena Samanta\, Ph.D.\nThe University of Texas at Austin \nExploiting the Fluorous Effect to Develop Adaptive Theranostic Devices in Oncology\nScott H. Medina\, Ph.D.\nCollege of Engineering\, The Pennsylvania State University \nChanging the shape of nanomedicines to enhance cancer immunotherapy\nDarrell J. Irvine\, Ph.D.\nThe Massachusetts Institute of Technology \nTargeting p27Kip1 in Cancer\nStacy Blain\, Ph.D.\nSUNY Downstate Medical Center; Chief Scientific Officer\, Concarlo Holding LLC \nAn Optical Nanosensor Platform for Cancer Detection and Monitoring\nRyan Williams\, Ph.D.\nThe City College of New York \nTunable composite nanocarriers for multi-modal imaging & theranostic applications\nNathalie May Pinkerton\, Ph.D.\nNew York University – Tandon School of Engineering \nUnderstanding and harnessing cell-material interactions in biomaterials\nThomas Pashuck\, Ph.D.\nLehigh University
URL:https://asrc.gc.cuny.edu/event/nanoscience-approaches-to-cancer/
LOCATION:Online
CATEGORIES:Nanoscience
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211013T120000
DTEND;TZID=America/New_York:20211013T130000
DTSTAMP:20260524T064856
CREATED:20210901T181813Z
LAST-MODIFIED:20211001T182521Z
UID:10001209-1634126400-1634130000@asrc.gc.cuny.edu
SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Marileen Dogterom\, Delft Univ of Technology Kavli Inst of Nanoscience
DESCRIPTION:Speaker: Professor\, Dept of Bionanoscience\, Delft Univ of Technology Kavli Inst of Nanoscience \nTitle: Reconstituting cytoskeletal systems in artificial cells \nAbstract: In my group we are interested in understanding how dynamic and force-generating properties of the\ncytoskeleton contribute to the spatial organization of cells. I will highlight recent advances (and challenges) in our efforts to reconstitute minimal\, functional cytoskeletal systems in artificial confinement. An example is the reconstitution of basic mitotic spindles in microfluidic droplets. These efforts fit in a long-term ambition to build\, in collaboration with others\, a minimal synthetic cell from scratch. \nParticipate via zoom \nDownload event flyer \nFor more information about this seminar and about joining in online\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-marileen-dogterom-delft-univ-of-technology-kavli-inst-of-nanoscience/
LOCATION:Online
CATEGORIES:Structural Biology
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211014T120000
DTEND;TZID=America/New_York:20211014T130000
DTSTAMP:20260524T064856
CREATED:20210930T150910Z
LAST-MODIFIED:20210930T150910Z
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SUMMARY:CUNY Academy for the Humanities and Sciences: Nir London\, Weizmann Institute
DESCRIPTION:To receive the Zoom link\, please send your name and affiliation to mphilipp@gc.cuny.edu. \nSpeaker: Nir London\, Ph.D.\, The Alan and Laraine Fischer Career Development Chair\, Department of Organic Chemistry\, Weizmann Institute of Science \nTitle: Crowdsourcing a Cure for COVID-19 \nAbstract: COVID-19\, caused by SARS-CoV-2\, lacks effective therapeutics. Additionally\, no antiviral drugs or vaccines were developed against the closely related coronavirus\, SARS-CoV-1 or MERS-CoV\, despite previous zoonotic outbreaks. To identify starting points for such therapeutics\, we performed a large-scale screen of electrophile and non-covalent fragments through a combined mass spectrometry and X-ray approach against the SARS-CoV-2 main protease. The results with more than 71 co-crystal structures that span the entire active site\, were released to the public and we implemented a crowd-sourcing platform to solicit next generation design ideas. Thousands of suggestions were submitted\, of which we made and tested >1\,500\, through a global consortium including academic labs\, chemical vendors\, pharma advisors and more. This effort resulted in <100nM inhibitors with crystallographic confirmation and activity in live virus assays. Crowd computing (Folding@Home) was harnessed for compound optimization; AI (via PostEra) for prioritization and retrosynthesis. This is still an on-going live project that can benefit from the input of medicinal chemists world-wide. We hope this initiative can serve as a template for an alternative drug discovery pipeline for areas that are unappealing to traditional pharma such as pandemic preparedness and antibiotic development. 
URL:https://asrc.gc.cuny.edu/event/cuny-academy-for-the-humanities-and-sciences-nir-london-weizmann-institute/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211018T120000
DTEND;TZID=America/New_York:20211018T130000
DTSTAMP:20260524T064856
CREATED:20210901T193404Z
LAST-MODIFIED:20210901T193428Z
UID:10001212-1634558400-1634562000@asrc.gc.cuny.edu
SUMMARY:Environmental Sciences Initiative AWAKES: Charles J. Vörösmarty\, CUNY ASRC & CCNY
DESCRIPTION:Speaker: Charles J. Vörösmarty\, Ph.D.\, Director\, Environmental Sciences Initiative\, CUNY Advanced Science Research Center at The Graduate Center\, Professor\, Dept. of Civil Engineering\, The City College of New York \nUpdates from the ASRC Environmental Sciences Initiative Research Groups 
URL:https://asrc.gc.cuny.edu/event/environmental-sciences-initiative-awakes-charles-j-vorosmarty-cuny-asrc-ccny/
LOCATION:ASRC 5th Floor Data Visualization Room\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Environmental Sciences
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211020T120000
DTEND;TZID=America/New_York:20211020T130000
DTSTAMP:20260524T064856
CREATED:20210901T195346Z
LAST-MODIFIED:20211008T203607Z
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SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Kathryn Wellen\, Univ of Pennsylvania
DESCRIPTION:Speaker: Kathryn Wellen\, Associate Professor\, Dept of Cancer Biology\, Univ of Pennsylvania \nTitle: Metabolic compartmentalization and adaptations in cancer \nAbstract: Cells continually monitor nutrient availability to adapt to their environment and to inform decisions about survival\, proliferation\, and performance of different functions. Accordingly\, many metabolites play crucial roles as signaling molecules\, in addition to their functions in energy production and biosynthesis. In this presentation\, I will discuss two projects. In the first\, I will discuss the application of new methods to assess metabolism in subcellular compartments such as the nucleus to glean new insights into mechanisms of crosstalk between metabolism and the epigenome. In the second\, I will discuss evidence for engagement of a hexosamine salvage mechanism that cancer cells employ in the face of nutrient deprivation in the tumor microenvironment. \nParticipate via zoom \nDownload event flyer \nFor more information about this seminar and about joining in online\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-kathryn-wellen-univ-of-pennsylvania/
LOCATION:Online
CATEGORIES:Structural Biology
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211027T120000
DTEND;TZID=America/New_York:20211027T130000
DTSTAMP:20260524T064856
CREATED:20210901T195704Z
LAST-MODIFIED:20210901T195704Z
UID:10001217-1635336000-1635339600@asrc.gc.cuny.edu
SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Nozomi Ando\, Cornell University
DESCRIPTION:Speaker: Nozomi Ando\, Associate Professor\, Dept of Chemistry & Chemical Biology\, Cornell University \nTitle: Cornell University \nAbstract: TBD \nFor more information about this seminar and about joining in online\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-nozomi-ando-cornell-university/
LOCATION:Online
CATEGORIES:Structural Biology
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211029T140000
DTEND;TZID=America/New_York:20211029T150000
DTSTAMP:20260524T064856
CREATED:20210811T200239Z
LAST-MODIFIED:20211019T133214Z
UID:10001201-1635516000-1635519600@asrc.gc.cuny.edu
SUMMARY:Science Careers Beyond the Lab: A Conversation With AAAS CEO Sudip Parikh
DESCRIPTION:This event is part of the Communicating Your Science series. \nThis series features presentations by The Graduate Center’s science librarian and communications staff\, journal editors\, and reporters. The goal of this series is to enhance the professional development and science communication skills of CUNY STEM faculty\, postdocs\, and students. Learn more » \n\na special session with AAAS CEO Sudip Parikh and Graduate Center\, CUNY Dean for the Sciences Joshua Brumberg\, who will discuss how a science Ph.D. can lead to careers beyond the lab\, especially in areas such as scientific journals and advocacy work aimed at shaping science policy\, improving STEM education\, diversifying the field and build bridges between researchers and the public. They will cover: \n\nParikh’s path to leading a scientific society\nThe role of AAAS as an advocacy organization and journal publisher\nAAAS student opportunities\n\nThere will be time for Q&A. \nRegister online now to participate » \nFor more information\, contact Shawn Rhea at srhea@gc.cuny.edu.
URL:https://asrc.gc.cuny.edu/event/science-careers-beyond-the-lab/
LOCATION:Online
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
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