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X-WR-CALDESC:Events for The Advanced Science Research Center
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DTSTART;TZID=America/New_York:20220315T120000
DTEND;TZID=America/New_York:20220315T130000
DTSTAMP:20260307T230956
CREATED:20210707T022753Z
LAST-MODIFIED:20220315T132754Z
UID:10001195-1647345600-1647349200@asrc.gc.cuny.edu
SUMMARY:Photonics Seminar: Joshua Caldwell\, Vanderbilt University
DESCRIPTION:Join us on March 15th\, for a one-hour talk presented by Joshua Caldwell\, PhD\, Director of the\nInterdisciplinary Materials Science Ph.D. Program at Vanderbilt University titled: \nStrong Coupling and Extreme Anisotropy in Infrared Polaritonic Media \nAbstract – The field of nanophotonics is based on the ability to confine light to subdiffractional dimensions. In the infrared\, this requires compression of the wavelength to length scales well below that of the free-space values. While traditional dielectric materials do not exhibit indices of refraction high enough in non-dispersive media to realize such compression\, the implementation of polaritons\, quasi-particles comprised of oscillating charges and photons\, enable such opportunities. Two predominant forms of polaritons\, the plasmon and phonon polariton\, which are derived from light coupled with free carriers or polar optic phonons\, respectively\, are broadly applied in the mid- to longwave infrared. However\, the short scattering lifetimes of free-carriers results in high losses and broad linewidths for the former\, while the fast dispersion and narrow band of operation for the latter result in significant limitations for both forms. \nHere we will discuss the opportunity to implement polaritonic strong coupling between different media in an effort to dictate the polaritonic dispersion relation\, and thus\, the propagation and resonant properties of these materials. Further\, by employing the extreme anisotropy of crystals ranging from two-dimensional materials such as hexagonal boron nitride and transition metal dichalcogenides to low-symmetry monoclinic to triclinic materials\, novel optical phenomena such as hyperbolicity and shear polaritons are observed. The talk will highlight ultra-strong coupling between both forms of polaritons in the context of infrared emitters\, as a means to control planar propagation using hyperbolic polaritons\, a modifying thermal dissipation at ultrafast time scales. \nBio – Prof. Joshua Caldwell is the Flowers Family Chancellor Faculty Fellow and Associate Professor of Mechanical Engineering and the current Director of the Interdisciplinary Materials Science Ph.D. Program at Vanderbilt University. He was awarded his Bachelor of Chemistry from Virginia Tech in 2000 before heading to the University of Florida where he received his PhD in Physical Chemistry in 2004. There he used magnetic resonance methods to investigate electron-nuclear spin coupling within low-dimensional quantum wells and heterostructures. He accepted a postdoctoral fellowship at the Naval Research Laboratory in 2005\, using optical spectroscopy as a means of understanding defects within wide-band gap semiconductors. He was transitioned to permanent staff in 2007\, where he began work in the field of nanophotonics\, investigating coupling phenomena within plasmonic materials. Prof. Caldwell merged his prior work in wide band gap semiconductor materials with his efforts in nanophotonics\, leading to his work exploiting undoped\, polar dielectric crystals for lowloss\, sub-diffractional infrared optics. He is a three-time recipient of the highly competitive NRL Nanoscience Institute grants and was promoted to senior (supervisory) staff at NRL in 2012. He was awarded a sabbatical at the University of Manchester with Prof. Kostya Novoselov in 2013-2014\, investigating the use of van der Waals crystals such as hexagonal boron nitride for mid-IR to THz nanophotonics\, where he demonstrated the natural hyperbolic response of this material. During his time at NRL he was a 4-time recipient of the Alan Berman Best Pure Science Paper Award and received the Thomas Edison Best Patent Award for his dry transfer technique for 2D materials. In 2017 he accepted a tenured Associate Professorship at Vanderbilt University within the Mechanical Engineering Department. He was elected as a Fellow of the Materials Research Society in 2020 and has published over 160 papers\, >8300 citations and 11 patents\, with two more pending. \n  \nFor more information about this hybrid event\, please contact: \nLeah Abraha \nPhotonics Initiative \nlabraha@gc.cuny.edu. \nZoom Access>>> \nMeeting ID: 889 5868 8719   \nPasscode: 281231 \nDial by your location: https://gc-cuny-edu.zoom.us/u/kdlagOlT9z \n 
URL:https://asrc.gc.cuny.edu/event/photonics-seminar-joshua-caldwell-vanderbilt-university-2/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Photonics
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220309T120000
DTEND;TZID=America/New_York:20220309T130000
DTSTAMP:20260307T230956
CREATED:20220302T214020Z
LAST-MODIFIED:20220302T214020Z
UID:10001241-1646827200-1646830800@asrc.gc.cuny.edu
SUMMARY:ASRC-CCNY Seminar Series in Biochemistry\, Biophysics and Biodesign: Nicholas K. Tonks
DESCRIPTION:Join us March 9th at 12pm\, for a one-hour talk presented by Nicholas K. Tonks\, Professor of Cancer Research; Dep. Director\, NCI-Cancer Center Cold Spring Harbor Laboratory\, Cold Spring Harbor\, NY\, titled: \nProtein Tyrosine Phosphatases and the Regulation of Cell Signaling: From Basic Research to New Therapeutics \nABSTRACT- The protein phosphatases are critical\, specific regulators of signaling that serve an essential function\, in a coordinated manner with the protein kinases\, to determine the response to a physiological stimulus. My laboratory takes a multidisciplinary approach to study the structure\, regulation and function of the protein tyrosine phosphatase (PTP) family of enzymes\, to illustrate their fundamental importance to the control of signal transduction under normal and pathophysiological conditions. As functional studies have established links to disease\, the PTPs have been garnering attention as potential therapeutic targets; however\, they remain a largely untapped resource for drug development. \nA focus of the lab is PTP1B\, the prototypic member of the PTP family that I discovered ~30 years ago. It is a validated target for diabetes and obesity\, as well as HER2-positive cancer\, and as such has been the subject of extensive drug discovery efforts. PTP1B is a challenging target for drug development\, which led industry to conclude that the members of the PTP family are “undruggable”. Consequently\, new approaches are required to exploit this important target effectively and reinvigorate drug discovery efforts. \nNow\, the detailed understanding of the structure and function of PTP1B\, which we have generated in an academic setting\, is revealing new approaches to the development of small molecule drug candidates. This includes small molecules that harness the physiological regulation of PTP function by reversible oxidation\, as well as allosteric inhibitors that stabilize an inactive conformation of PTP1B that is encountered in the absence of substrate and chelate copper specifically. These studies have opened up unanticipated ways to modulate the activity of critical signaling pathways in vivo. The application of these inhibitors is now revealing new functions of PTP1B and suggesting new indications in which these molecules may be applied for therapeutic benefit. \n  \nThis seminar will be presented via Zoom\, the broadcast can also be viewed in the ASRC Auditorium. \nTo join these ongoing events\, the zoom link can also be found below: \nJoin Zoom Meeting\nMeeting ID: 495 404 8198 \nFor more information about this hybrid event please contact: \nHyacinth Camillieri \nhcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-and-biodesign-nicholas-k-tonks/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
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END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220307T113000
DTEND;TZID=America/New_York:20220307T123000
DTSTAMP:20260307T230956
CREATED:20220223T170351Z
LAST-MODIFIED:20220228T055053Z
UID:10001239-1646652600-1646656200@asrc.gc.cuny.edu
SUMMARY:Photonics Seminar: Kai Wang\, Stanford University
DESCRIPTION:Title: New paradigms of photonic state manipulation on synthetic platforms  \nAbstract – Photons\, the particles of light\, are ideal carriers of quantum and classical information. My research focuses on employing fundamental physics concepts and advanced photonics technology for the unconventional manipulation of photons in their intrinsic degrees of freedom\, from polarization to spatial modes to frequency. \nThe first part of the talk will be on nanostructured metasurfaces for quantum photonics. I will show our experimental results that use metasurfaces for the interference\, tomographic measurement\, and nontrivial transformation of multiphoton quantum states encoded in the polarization degree of freedom. \nThe second part will focus on non-Hermitian topological photonics in synthetic dimensions. I will show how we implement lattice Hamiltonians with unprecedented flexibility using discrete frequency modes of photons in a dynamically modulated system. I will show how we judiciously use losses to achieve non-Hermitian topological invariants\, from nontrivial winding numbers to braids/knots formed by the complex-energy non-Hermitian bands. \nThe last part of my talk will show where my works and expertises point to in the future. I will briefly share my visions and plans on developing scalable quantum interconnect and simulation platforms based on new paradigms of manipulation of multidimensional photonic states encoded in intrinsic degrees of freedom. \nBio – Kai Wang is currently a Postdoctoral Scholar in the Department of Electrical Engineering at Stanford University. Before Stanford\, he received his PhD from The Australian National University in 2019. Prior to that\, he obtained MSc from Friedrich-Schiller-Universität Jena and BE from Tianjin University. His research interests include quantum photonics\, non-Hermitian topological photonics\, and metasurfaces. \n  \nFor more information about this hybrid event\, please contact: \nDiana Strickland \nPhotonics Initiative \ndstrickland@gc.cuny.edu \nZoom Access>>> \nMeeting ID: 810 5653 1420 \nPasscode: 116074 \n 
URL:https://asrc.gc.cuny.edu/event/photonics-seminar-kai-wang-stanford-university/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Photonics
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220303T140000
DTEND;TZID=America/New_York:20220303T153000
DTSTAMP:20260307T230956
CREATED:20220214T163125Z
LAST-MODIFIED:20220301T173834Z
UID:10001230-1646316000-1646321400@asrc.gc.cuny.edu
SUMMARY:Epigenetics Core Workshop Series: Introducing 10X Chromium
DESCRIPTION:  \nPlease join us March 3rd\, 2022\, for an introductory seminar on the workflow of our newest instrument addition at the Epigenetics Core of ASRC – 10 Chromium iX Controller. \nKrunal Shah from 10x Genomics Inc. will present a talk titled: \nIntroducing 10X Chromium \n   – Single Cell Gene Expression Solution with Feature Barcode Technology \nSingle cell analysis has been a revolutionary breakthrough in biology. Understanding cellular diversity has enabled significant insights into intracellular mechanisms and their applications to health and disease (Learn More…) \n  \n  \nPlease register for the event here. \nTo access the Zoom. \nFor further details\, contact:\nJia Liu at Epigenetics Core Facility\n212.413.3183\nEmail: jliu1@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/epigenetics-core-workshop-series/
LOCATION:Online
CATEGORIES:Neuroscience
ATTACH;FMTTYPE=image/jpeg:https://asrc.gc.cuny.edu/wp-content/uploads/media/event/epigenetics-core-workshop-series/Draft-Epigenetics-Core-Workshop-Series.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220302T120000
DTEND;TZID=America/New_York:20220302T130000
DTSTAMP:20260307T230956
CREATED:20220214T182900Z
LAST-MODIFIED:20220301T174212Z
UID:10001232-1646222400-1646226000@asrc.gc.cuny.edu
SUMMARY:ASRC-CCNY Seminar Series in Biochemistry\, Biophysics and Biodesign: Shelley D. Minteer\, University of Utah
DESCRIPTION:Join us March 2nd at 12pm\, for a one-hour talk presented by Shelley D. Minteer\, Professor in the Dept. of Chemistry and Dept. of Materials Science & Engineering\, University of Utah\, Salt Lake City\, UT titled: \nBioelectrocatalysis for Electrosynthesis \nAbstract- In the last 5 years\, there have been extensive studies and new materials designed for interfacing biocatalysts with electrode surfaces. This talk will discuss electroanalytical techniques for studying biocatalysis\, including both mediated bioelectrocatalysis and direct bioelectrocatalysis. The talk will discuss electrode materials innovation for interfacing complex proteins with electrode surfaces as well as using them for electrosynthesis of ammonia as well as other value-added products (i.e.\, chiral amines\, chiral amino acids\, polymers\, etc.). This talk will discuss strategies for cofactor regeneration. Finally\, this talk will discuss the use of synthetic biology for microbial bioelectrosynthesis of ammonia and other value-added products. \n  \nThis seminar will be presented via Zoom\, the broadcast can also be viewed in the ASRC Auditorium. \nTo join these ongoing events\, the zoom link can also be found below: \nJoin Zoom Meeting\nMeeting ID: 495 404 8198 \nFor more information about this hybrid event please contact: \nHyacinth Camillieri \nhcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-and-biodesign-shelley-d-minteer-university-of-utah/
LOCATION:Advanced Science Research Center (ASRC)\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
ATTACH;FMTTYPE=image/jpeg:https://asrc.gc.cuny.edu/wp-content/uploads/media/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-and-biodesign-shelley-d-minteer-university-of-utah/SBI-Seminar-website-image-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220302T103000
DTEND;TZID=America/New_York:20220302T113000
DTSTAMP:20260307T230957
CREATED:20220217T170309Z
LAST-MODIFIED:20220228T060103Z
UID:10001234-1646217000-1646220600@asrc.gc.cuny.edu
SUMMARY:Photonics Seminar: Qiushi Guo\, California Institute of Technology\, Yale University
DESCRIPTION:Join us March 2nd at 10:30am\, for a one-hour talk from Dr. Qiushi Guo\, California Institute of Technology\, Yale University. \nTitle- Emergent active photonic platforms for next-generation mid-infrared and ultrafast photonics \nAbstract – As two basic properties of light\, wavelength and timescale are central to numerous photonic applications. Compared to visible and near-infrared\, the longer wavelength mid-infrared spectral regime contains unique thermal visual information and chemical fingerprints of the environment. On a different front\, femtosecond light sources and systems can enable ultrafast information processing\, sensing\, and computing. Yet\, current chip-scale photonic devices and systems are facing tremendous challenges in detecting\, generating\, and processing light of long wavelength and ultrashort timescale. Overcoming these challenges requires new materials and clever device architectures\, and these technologies stand poised to evolutionize fields such as biomedical sensing\, free-space communication\, and photonic computing in both classical and quantum domains. \nIn this talk\, I will show that by engineering the carrier and nonlinear dynamics in emergent active photonic materials\, we can detect photons beyond the regimes accessible to conventional laser sources and detectors\, and process information in an ultrafast manner. In the first half of my talk\, I will first briefly introduce the discovery of black phosphorus (BP) mid-infrared photonics\, highlighting the world’s first BP mid-infrared detectors with high internal gain\, as well as BP’s electrically tunable spectral response due to its unique bandgap tunability. Then\, I will discuss a new strategy for detecting longer wavelength mid-infrared radiations at 12 µm. This is achieved by harnessing the intrinsic mid-infrared plasmons in large-scale graphene. \nThe second half of my talk will cover my recent work on integrated lithium niobate (LN) ultrafast photonics in both classical and quantum domains. I will discuss the realization of ultra-strong nonlinear optical interactions and dynamics in dispersion-engineered and quasi-phase-matched integrated LN devices\, which have enabled 100 dB/cm optical parametric amplification\, ultra-wide bandwidth quantum squeezing\, as well as femtosecond and femtojoule all-optical switching. Finally\, I will outline promising pathways toward realizing chip-scale ultrafast light sources and microsystems for on-chip spectroscopic sensing\, mid-infrared free-space communication\, coherent all-optical computing\, and next-generation thermal vision technologies. \nBio – Dr. Qiushi Guo is currently a postdoctoral scholar at the California Institute of Technology with Prof. Alireza Marandi. He received his Ph.D. in Electrical Engineering from Yale University in Dec. 2019\, advised by Prof. Fengnian Xia. He received his M.S. degree in Electrical Engineering from the University of Pennsylvania in 2014\, and his B.S. degree in Electrical Engineering from Xi’an Jiaotong University in 2012. Qiushi is the winner of the 2021 Henry Prentiss Becton Graduate Prize for his exceptional research achievements at Yale University. His research interests include integrated nonlinear and quantum photonics\, mid-infrared photonics\, and 2-D materials optoelectronics. He has published 36 peer-reviewed research papers in leading scientific journals with citations more than 2700 times. He is serving on the editorial board of the journal Micromachines. \n  \nFor more information about this hybrid event\, please contact: \nDiana Strickland \nPhotonics Initiative \ndstrickland@gc.cuny.edu \nZoom Access>>> \nMeeting ID: 826 5500 2741 \nPasscode: 793645
URL:https://asrc.gc.cuny.edu/event/photonics-seminar-qiushi-guo-california-institute-of-technology-yale-university/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Photonics
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220228T113000
DTEND;TZID=America/New_York:20220228T123000
DTSTAMP:20260307T230957
CREATED:20220218T201016Z
LAST-MODIFIED:20220228T055346Z
UID:10001238-1646047800-1646051400@asrc.gc.cuny.edu
SUMMARY:Photonics Seminar: Kiyoul Yang\, Stanford University
DESCRIPTION:Title: Building photonic systems for extreme-scale computing\, particle accelerations\, and\nbeyond \nAbstract – A photonic-electronic system can potentially process enormous amounts of data that no stand-alone electronics have been capable of. Furthermore\, a chip-scale optical atomic clock can be so precise that it only loses the equivalent of one second every million years. In the foreseeable future\, highly integrated photonics can usher disruptive advances in communications\, deep learning\, and atomic-photonic integration. \n  \nTo realize this vision\, my research has built multi-levels of the photonic system stacks from discrete nanophotonic devices\, all the way to creating advanced system-level demonstrations. In this talk\, I will introduce recent experiments where we demonstrate natively error-free terabit/s data transmission using integrated frequency combs and multi-dimensional silicon photonics circuits [1]. The frequency comb device transduces a narrow linewidth laser into a series of replicas over hundreds of frequency modes [2]. We employed photonic inverse design for wavelength and spatial multiplexing to enable bandwidth density on silicon photonic circuits to be three orders of magnitude higher than that of optical fibers. \n  \nI will conclude my talk with applications and prospects for large-scale photonic systems that can manipulate atoms\, ions\, and free electrons\, along with preliminary studies on UV-visible nonlinear optics and laser particle accelerations on a chip [3]. \n  \n[1] K.Yang\, et al.\, arXiv: 2103.14139 (2021). \n[2] K.Yang\, et al.\, Nature Photonics 12\, 297 – 302 (2018); M.Guidry*\, D.Lukin*\, K.Yang*\, et al.\, Nature Photonics 16\, 52 – 58 (2022). \n[3] D.Oh*\, K.Yang*\, et al.\, Nature Communications 8\, 13922 (2017); N.Sapra\, K.Yang\, et al.\, Science 367\, 79 – 83 (2020). \n  \nBio – Kiyoul Yang is a research scientist at Stanford University working with Prof. Jelena Vuckovic\, and holds a PhD in Electrical Engineering from the California Institute of Technology (2018). He is a recipient of the Paul F. Forman Team Engineering Excellence Award (2020) for the 2-photon optical clock collaboration. He serves as a vice-chair of the technical program committee of IEEE Photonics Conference\, and a co-editor for the special issue of ACS Photonics. \n  \nFor more information about this hybrid event\, please contact: \nDiana Strickland \nPhotonics Initiative \ndstrickland@gc.cuny.edu \nZoom Access>>> \nMeeting ID: 821 0040 3904 \nPasscode: 892411
URL:https://asrc.gc.cuny.edu/event/photonics-seminar-kiyoul-yang-stanford-university/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Photonics
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220225T140000
DTEND;TZID=America/New_York:20220225T150000
DTSTAMP:20260307T230957
CREATED:20210811T204246Z
LAST-MODIFIED:20220208T181908Z
UID:10001204-1645797600-1645801200@asrc.gc.cuny.edu
SUMMARY:CUNY STEM Opportunities for Mastering Science Outreach
DESCRIPTION:CUNY STEM Opportunities for Mastering Science Outreach \nIn popular culture\, nearly all the focus is placed on the research part of scientists’ work. But the efforts scientists make to engage the public\, creating an interest in and support for the field\, is critical to the STEM pipeline and ensuring that research addresses social priorities.  \nJoin us at 2 p.m. on Friday\, Feb. 25 for our next Communicating Your Science event where we will explore opportunities for engaging in and mastering science outreach. The panel will be led by Kendra Krueger (4loveandscience.com)\, the CUNY ASRC’s STEM Outreach and Education Manager and founder of the Community Sensor Lab\, and will feature other special guests. Krueger has a BS and MS in electrical engineering and has worked as an educator\, artist and community organizer.  \nThere will be time for Q&A.  \nSign-up today for this month’s Communicating Your Science event and check out the new Graduate Center Science Communications Academy webpage\, where you can learn about our events and access science communications training tools.
URL:https://asrc.gc.cuny.edu/event/meet-the-editor-cuny-faculty-stem-journal-editors/
LOCATION:Online
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
ATTACH;FMTTYPE=image/jpeg:https://asrc.gc.cuny.edu/wp-content/uploads/media/events/communicating-your-science-series/Graduate-Center-Science-Academy-Main-Banner_v2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220223T120000
DTEND;TZID=America/New_York:20220223T130000
DTSTAMP:20260307T230957
CREATED:20220214T162133Z
LAST-MODIFIED:20220222T165000Z
UID:10001228-1645617600-1645621200@asrc.gc.cuny.edu
SUMMARY:ASRC-CCNY Seminar Series in Biochemistry\, Biophysics and Biodesign: W. Seth Childers\, University of Pittsburgh
DESCRIPTION:Join us February 23rd at 12pm for a one-hour talk presented by W. Seth Childers\, Assistant Professor\, Department of Chemistry\, University of Pittsburgh\, Pittsburgh\, PA\, titled: \nBiomolecular condensates as organizers of biochemistry in bacteria \nAbstract- One defining difference between bacteria and eukaryotes is the absence of membrane-bound organelles in bacteria. Recently\, a second fundamental compartmentalization strategy in eukaryotes has been recognized that relies upon phase separation of scaffolding proteins. These assemblies lack a membrane barrier but can organize and sequester biochemistry as a “membraneless organelle.” Here\, we will describe our discoveries of how biomolecular condensates organize and regulate mRNA decay and signal transduction processes in bacteria. Overall\, our discoveries combined with those from other labs suggest a new image of bacteria as a “bag of biomolecular condensates.” One significant challenge in cell biology is understanding if these membraneless organelles have any functional significance? Towards this goal\, the Childers lab has characterized how phase separation impacts ribonuclease and kinase enzyme kinetics in vitro. They found that activation of a signaling protein’s function was coupled to phase separation of the signaling complex\, which may present a generalizable way to regulate low copy signaling in cells in an all-or-none fashion. To consider the function of biomolecular condensates in vivo\, the Childers lab has developed a fluorescence biosensor imaging strategy that visualized how membraneless organelles impact the structure of a bacterial signaling protein critical for asymmetric cell division in Caulobacter crescentus. Finally\, the Childers lab applied a chemical genetics approach to interrogate the importance of phase separation towards bacterial physiology. They identified a small molecule that inhibits phase separation of an essential bacterial biomolecular condensate that regulates chromosome segregation. In summary\, our studies suggest that phase separation provides bacteria with a generalizable compartmentalization strategy\, and disruption of phase separation may present an actionable antibiotic target. \n  \nThis seminar will be presented via Zoom\, the broadcast can also be viewed in the ASRC Auditorium. \nTo join these ongoing events\, the zoom link can also be found below: \nJoin Zoom Meeting\nMeeting ID: 495 404 8198 \nFor more information about this hybrid event please contact: \nHyacinth Camillieri \nhcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-and-biodesign-2/
LOCATION:Advanced Science Research Center (ASRC)\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
ATTACH;FMTTYPE=image/jpeg:https://asrc.gc.cuny.edu/wp-content/uploads/media/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-and-biodesign-shelley-d-minteer-university-of-utah/SBI-SEMINAR-SERIES-Website-Image.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220216T120000
DTEND;TZID=America/New_York:20220216T130000
DTSTAMP:20260307T230957
CREATED:20220214T143243Z
LAST-MODIFIED:20220214T193415Z
UID:10001107-1645012800-1645016400@asrc.gc.cuny.edu
SUMMARY:ASRC-CCNY Seminar Series in Biochemistry\, Biophysics and Biodesign: Filip Van Petegem\, University of British Columbia
DESCRIPTION:  \nJoin us Feb. 16th at 12pm\, for a one-hour talk presented by Filip Van Petegem\, Professor in the Dept. of Biochemistry & Molecular Biology\, University of British Columbia\, Vancouver\, Canada titled: \nChannelopathies at high resolution: Cryo-EM and crystallographic investigation of cardiac and skeletal muscle ion channels \n  \nThis seminar will be presented via Zoom\, the broadcast can also be viewed in the ASRC Auditorium. \nFor more information about this hybrid event\, including an abstract from the speaker and to access the zoom link\, please see the event flyer. \n  \nFor further questions please contact: \nHyacinth Camillieri at hcamillieri@gc.cuny.edu \nTo quicker join these ongoing events\, the zoom link can also be found below at: \nJoin Zoom Meeting\nMeeting ID: 495 404 8198
URL:https://asrc.gc.cuny.edu/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-and-biodesign/
LOCATION:Advanced Science Research Center (ASRC)\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
ATTACH;FMTTYPE=image/jpeg:https://asrc.gc.cuny.edu/wp-content/uploads/media/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-and-biodesign-shelley-d-minteer-university-of-utah/SBI-SEMINAR-SERIES-Website-Image.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220209T120000
DTEND;TZID=America/New_York:20220209T130000
DTSTAMP:20260307T230957
CREATED:20220127T064244Z
LAST-MODIFIED:20220204T165005Z
UID:10001105-1644408000-1644411600@asrc.gc.cuny.edu
SUMMARY:ASRC- CCNY Seminar Series in Biochemistry\, Biophysics and Biodesign
DESCRIPTION:As the first speaker in this series\, Sjors Scheres\, Structural Studies Division at the MRC Laboratory of Molecular Biology at Cambridge University\, Cambridge\, UK\, will present a one-hour talk titled: \n Cryo-EM Structures of Amyloids from the Human Brain \nIn it\, he will give an introduction to the basics of cryo-EM structure determination and explain how such structures have revealed unexpected differences between the tau filaments from the different diseases\, and how these provide exciting avenues to unravel the mechanisms of amyloid formation in neurodegeneration. Following the talk will be time for a Q & A. \nFor more information about this hybrid event\, including an abstract from the guest speaker and to access the zoom link\, please access the event flyer. \nFor further questions please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu \n  \nTo quicker access these ongoing events\, the zoom link can also be found below at: \nJoin Zoom Meeting\nMeeting ID: 495 404 8198
URL:https://asrc.gc.cuny.edu/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-biodesign/
LOCATION:Online
CATEGORIES:Structural Biology
ATTACH;FMTTYPE=image/png:https://asrc.gc.cuny.edu/wp-content/uploads/media/event/asrc-ccny-seminar-series-in-biochemistry-biophysics-biodesign/SBI-SEMINAR-SERIES-Email-Banner.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220128T140000
DTEND;TZID=America/New_York:20220128T150000
DTSTAMP:20260307T230957
CREATED:20210811T203048Z
LAST-MODIFIED:20230314T165323Z
UID:10001203-1643378400-1643382000@asrc.gc.cuny.edu
SUMMARY:Easy Science Videos With Lumen5 & iPhones
DESCRIPTION:This event is part of the Communicating Your Science series. \nThis series features presentations by The Graduate Center’s science librarian and communications staff\, journal editors\, and reporters. The goal of this series is to enhance the professional development and science communication skills of CUNY STEM faculty\, postdocs\, and students. Learn more » \n\nEasy Science Videos With Lumen5 & iPhones\nA short\, well-crafted video is an ideal tool for making science exciting\, relatable and understandable for a variety of audiences. And\, with a few simple tools and production tips\, they can be easy to create. \nJoin us on Friday\, January 28 at 2 p.m. for our next edition of Communicating Your Science where we will explore how you can create short science videos that convey your research in clear and compelling ways without a lot of effort. Our In-house experts will cover: \n\nTips for shooting and editing videos on your phone.\nHow to use Canva to create and share science videos\nShooting\, editing and sharing videos on Tik Tok.\nGeneral tips for sharing on social media.\n\nThere will be time for Q&A. \nYou can sign-up here for this month’s Communicating Your Science event. \nCheck out the new Graduate Center Science Communications Academy webpage\, where you can learn about our events and access science communications training tools. \n\nThis event has passed. Watch the video recording below:
URL:https://asrc.gc.cuny.edu/event/easy-science-videos-with-lumen5-iphones/
LOCATION:Online
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
ATTACH;FMTTYPE=image/jpeg:https://asrc.gc.cuny.edu/wp-content/uploads/media/events/communicating-your-science-series/Graduate-Center-Science-Academy-Main-Banner_v2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20220120T100000
DTEND;TZID=America/New_York:20220120T110000
DTSTAMP:20260307T230957
CREATED:20220112T171841Z
LAST-MODIFIED:20220112T172933Z
UID:10001103-1642672800-1642676400@asrc.gc.cuny.edu
SUMMARY:Converge to Transform Interdisciplinary STEM Seminar Series
DESCRIPTION:Converge to Transform: Interdisciplinary STEM Seminar Series\n  \n​​​​​​January 20th\n10 am to 11am via Zoom\nJoin us for the next speaker in this series: Benjamin A Garcia\, PhD\, Raymond H. Wittcoff Distinguished Professor and Head of the Department of Biochemistry and Molecular Biophysics at the Washington University School of Medicine\, in St. Louis. Dr. Garcia will present a talk titled: \nQuantitative Proteomics for Understanding Cancer Epigenetics \nIn it he will describe how histones\, small proteins that package DNA into chromosomes\, control gene expression\, are regulated by epigenetic mechanisms\, and play a role in cancer when dysregulated. \nDr. Garcia’s research has led to important observations about the regulation of cell differentiation\, growth of tissues\, and the development of cancer. The Garcia Lab specializes in high-throughput and quantitative analysis of many classes of modified proteins but are particularly interested in understanding the roles of proteins PTMs during cancer pathogenesis\, neurodegeneration\, cell differentiation and viral infection. Such analyses can shed light on basic biology and disease processes. His methods have revolutionized analysis of proteins and genetics of cells from animal models and human samples. Such research has led to important observations about the regulation of cell differentiation\, growth of tissues\, and the development of cancer. In addition to cancer\, his lab studies the role and regulation of epigenetics in neurodegenerative diseases\, such as Alzheimer’s disease. \nThe seminar will be held virtually\, therefore please register here\, before 9am on Thursday January 20th. Please contact asrc.event@gc.cuny.edu with any questions. \n 
URL:https://asrc.gc.cuny.edu/event/converge-to-transform-interdisciplinary-stem-seminar-series/
LOCATION:Online
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
ATTACH;FMTTYPE=image/png:https://asrc.gc.cuny.edu/wp-content/uploads/media/event/converge-to-transform-interdisciplinary-stem-seminar-series/Converge-to-Transform-Interdisciplinary-STEM-Seminar-Series.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211209T160000
DTEND;TZID=America/New_York:20211209T180000
DTSTAMP:20260307T230957
CREATED:20211202T160231Z
LAST-MODIFIED:20211202T160231Z
UID:10001100-1639065600-1639072800@asrc.gc.cuny.edu
SUMMARY:CUNY Women in STEM: Building Our Network
DESCRIPTION:Join us for a professional development and networking event open to all CUNY graduate students\, postdoctoral fellows\, and faculty interested in furthering their STEM academic research careers!\nThursday\, December 9\, 2021\n4:00 pm to 6:00 pm \nTen CUNY faculty members and administrative leaders will talk about gender equity and inclusion in STEM\, with an emphasis on academia\, and give advice and tips on how to thrive and succeed. The audience will also have the opportunity to meet colleagues from across CUNY’s campuses during breakout sessions. \nThe event’s participants include:​​​​ \n\nPatrizia Casaccia\, M.D.\, Ph.D.\, Einstein Professor and Initiative Director\, Advanced Science Research Center\, The Graduate Center\nSaavik Ford\, Ph.D.\, Professor\, Borough of Manhattan Community College\nNina Gray\, Ph.D.\, Executive Director and Associate Dean\, Advanced Science Research Center\, The Graduate Center\nMandë Holford\, Ph.D.\, Associate Professor\, Hunter College\nDelaram Kahrobaei\, Ph.D.\, University Dean for Research\nKendra Krueger\, M.S.\, STEM Education and Outreach Manager\, Advanced Science Research Center\, The Graduate Center\nTamera Schneider\, Ph.D.\, Associate Vice Chancellor for Research\nChristina Sormani\, Ph.D.\, Professor\, Lehman College\nYingli Tian\, Ph.D.\, Distinguished Professor\, City College of New York\nRosemarie Wesson\, Ph.D.\, P.E.\, Interim Associate Provost for Research\, City College of New York\n\nPlease register here for the virtual event by December 8. \nOrganized by the CUNY Office of Research.
URL:https://asrc.gc.cuny.edu/event/cuny-women-in-stem-building-our-network/
LOCATION:Online
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
ATTACH;FMTTYPE=image/jpeg:https://asrc.gc.cuny.edu/wp-content/uploads/media/event/cuny-women-in-stem-building-our-network/2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211208T120000
DTEND;TZID=America/New_York:20211208T130000
DTSTAMP:20260307T230957
CREATED:20210901T201103Z
LAST-MODIFIED:20211118T185132Z
UID:10001226-1638964800-1638968400@asrc.gc.cuny.edu
SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Samuel Sternberg\, Columbia University Medical Ctr
DESCRIPTION:Speaker: Samuel Sternberg\, Assistant Professor\, Dept of Biochem. & Molecular Biophysics\, Columbia University\nMedical Ctr \nTitle: Evolutionary and mechanistic diversity of CRISPR RNA-guided transposases \nAbstract: Conventional CRISPR–Cas systems maintain genomic integrity by leveraging guide RNAs for the nuclease-dependent degradation of mobile genetic elements\, including plasmids and viruses. In a remarkable inversion of this paradigm\, bacterial transposons have coopted nuclease-deficient CRISPR–Cas systems to catalyze RNA-guided integration of mobile genetic elements into the genome. Here we show that programmable transposition occurs at a fixed distance downstream of target DNA sequences\, accommodates variable length genetic payloads\, and functions robustly in diverse bacterial species. Deep sequencing experiments reveal highly specific\, genome-wide DNA integration\, which is enabled by the coordinated and sequential recruitment of transposase factors to target sites specified by Cascade. By exploring a large set of evolutionarily diverse CRISPR-transposon systems\, we further define key sequence motifs that establish transposase-transposon specificity during DNA excision and integration. The discovery of a fully programmable\, RNA-guided transposase lays the foundation for kilobase-scale genome engineering that obviates the requirements for DNA double-strand breaks and homologous recombination. \nDownload flyer \nParticipate via Zoom » \nFor more information about this seminar\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-samuel-sternberg-columbia-university-medical-ctr/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211203T140000
DTEND;TZID=America/New_York:20211203T150000
DTSTAMP:20260307T230957
CREATED:20210811T201758Z
LAST-MODIFIED:20211118T214740Z
UID:10001202-1638540000-1638543600@asrc.gc.cuny.edu
SUMMARY:Sharing Your Research Through Images & Graphics
DESCRIPTION:This event is part of the Communicating Your Science series. \nThis series features presentations by The Graduate Center’s science librarian and communications staff\, journal editors\, and reporters. The goal of this series is to enhance the professional development and science communication skills of CUNY STEM faculty\, postdocs\, and students. Learn more » \n\nFrom journal publications to news stories and social media shares\, powerful images are essential to engaging and helping audiences understand new science. \nJoin us for an exciting edition of Communicating Your Science where our expert panel will explore tips and tools for creating graphics and other visuals that convey your research findings to diverse audiences in clear and compelling ways. Hear from: \n\nEd Bell\, a STEM graphic artist and animator\, and the former art director for Scientific American.\nSara Fresard\, a PhD student with the CUNY Graduate Center Biology program and a currentLennihan Arts & Science grantee who is researching how art-based practices can humanize science.\nFloor Grootenhuis\, an artist-in-residence at the Raper Lab at Hunter College where she works with researchers to help them translate their science into a visual language.\n\nThere will be time for Q&A. \nYou can sign-up here for this month’s Communicating Your Science event. \nFor more information\, contact Shawn Rhea at srhea@gc.cuny.edu.
URL:https://asrc.gc.cuny.edu/event/sharing-your-research-through-images-and-graphics/
LOCATION:Online
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
ATTACH;FMTTYPE=image/jpeg:https://asrc.gc.cuny.edu/wp-content/uploads/media/events/communicating-your-science-series/Graduate-Center-Science-Academy-Main-Banner_v2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211201T120000
DTEND;TZID=America/New_York:20211201T130000
DTSTAMP:20260307T230957
CREATED:20210901T200814Z
LAST-MODIFIED:20211118T183928Z
UID:10001224-1638360000-1638363600@asrc.gc.cuny.edu
SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Neel H. Shah\, Columbia University
DESCRIPTION:Speaker: Neel H. Shah\, Assistant Professor\, Department of Chemistry\, Columbia University \nTitle: Sequence-dependent tuning of inputs and outputs in phosphotyrosine signaling \nAbstract: Signal transduction through protein tyrosine phosphorylation is critical for many core functions of animal cells\, including proliferation\, survival\, programmed death\, and cell-cell communication. These processes are mediated by two large enzyme families\, tyrosine kinases and tyrosine phosphatases\, that collectively control the phosphorylation states of thousands of sites in human proteins. While it is well-established that tyrosine kinases and phosphatases can engage phosphorylation sites in a sequence dependent manner\, we know surprisingly little about how the sequences of phosphosites actually shape and tune signaling pathways. In this talk\, I will describe a high-throughput biochemical platform that we have developed to profile the sequence specificities of phosphotyrosine signaling proteins. I will discuss how this technique has yielded new insights into T cell activation and how it can be used for the large-scale characterization of disease-associated mutations proximal to tyrosine phosphorylation sites. Finally\, I will describe our efforts to understand the sequence-dependent activation of signaling enzymes bearing phosphotyrosine-recognition domains. \nDownload flyer \nParticipate via Zoom » \nFor more information about this seminar\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-neel-h-shah-columbia-university/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211129T120000
DTEND;TZID=America/New_York:20211129T130000
DTSTAMP:20260307T230957
CREATED:20210901T194115Z
LAST-MODIFIED:20210901T194115Z
UID:10001215-1638187200-1638190800@asrc.gc.cuny.edu
SUMMARY:Environmental Sciences Initiative AWAKES: Dianne Greenfield\, CUNY ASRC & Queens College
DESCRIPTION:Speaker: Dianne Greenfield\, Ph.D.\, Assoc. Professor\, CUNY Advanced Science Research Center at The Graduate Center\, Environmental Sciences Initiative and Earth and Environmental Sciences\, Queens College \nUpdates from the ASRC Environmental Sciences Initiative Research Groups 
URL:https://asrc.gc.cuny.edu/event/environmental-sciences-initiative-awakes-dianne-greenfield-cuny-asrc-queens-college/
LOCATION:ASRC 5th Floor Data Visualization Room\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Environmental Sciences
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211117T120000
DTEND;TZID=America/New_York:20211117T130000
DTSTAMP:20260307T230957
CREATED:20210901T200605Z
LAST-MODIFIED:20210901T200605Z
UID:10001222-1637150400-1637154000@asrc.gc.cuny.edu
SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Raghavendar (Raghu) Sanganna Gari\, Weill Cornell Medicine
DESCRIPTION:Speaker: Raghavendar (Raghu) Sanganna Gari\, Postdoctoral Associate\, Anesthesiology\, Weill Cornell Medicine \nTitle: Correlation of membrane protein dynamics with function \nAbstract: TBD \nFor more information about this seminar and about joining in online\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-raghavendar-raghu-sanganna-gari-weill-cornell-medicine/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211117T110000
DTEND;TZID=America/New_York:20211117T120000
DTSTAMP:20260307T230957
CREATED:20211102T133833Z
LAST-MODIFIED:20211102T133833Z
UID:10001098-1637146800-1637150400@asrc.gc.cuny.edu
SUMMARY:Advances in Battery Technology for Grid Storage\, Electric Vehicles\, and Wearable Electronics
DESCRIPTION:Tau Joint Seminar CUNY Energy Institute \nAdvances in Battery Technology for Grid Storage\, Electric Vehicles\, and Wearable Electronics \nSpeakers: Emanuel Peled\, Ph.D.\, Professor Emeritus\, Chemistry\, Tel-Aviv University and Diana Golodnitsky\, Ph.D.\, The Raymond and Beverly Sackler Chair in Chemistry and Energy Sciences\, Tel Aviv University. \nRegister in advance here: https://ccny.zoom.us/meeting/register/tZYldO6urTotGtG9fVTVKXZ0IlRp5K0sipVR \nCo-sponsored by: CUNY Energy Institute\, CCNY Grove School of Engineering\, CUNY ASRC\, and CUNY
URL:https://asrc.gc.cuny.edu/event/advances-in-battery-technology-for-grid-storage-electric-vehicles-and-wearable-electronics/
LOCATION:Online
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211115T120000
DTEND;TZID=America/New_York:20211115T130000
DTSTAMP:20260307T230957
CREATED:20210901T193937Z
LAST-MODIFIED:20210901T194347Z
UID:10001214-1636977600-1636981200@asrc.gc.cuny.edu
SUMMARY:Environmental Sciences Initiative AWAKES: Andrew Reinmann\, CUNY ASRC & Hunter College
DESCRIPTION:Speaker: Andrew Reinmann\, Ph.D.\, Asst. Professor\, CUNY Advanced Science Research Center at The Graduate Center\, Asst. Professor of Geography\, Hunter College \nUpdates from the ASRC Environmental Sciences Initiative Research Groups 
URL:https://asrc.gc.cuny.edu/event/environmental-sciences-initiative-awakes-andrew-reinmann-cuny-asrc-hunter-college/
LOCATION:ASRC 5th Floor Data Visualization Room\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Environmental Sciences
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211110T120000
DTEND;TZID=America/New_York:20211110T130000
DTSTAMP:20260307T230957
CREATED:20210901T200247Z
LAST-MODIFIED:20211105T155356Z
UID:10001220-1636545600-1636549200@asrc.gc.cuny.edu
SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Eduardo Torres\, Univ of Massachusetts Medical School
DESCRIPTION:Speaker: Eduardo Torres\, Assistant Professor\, Dept of Molecular\, Cell & Cancer Biology\, Univ of Massachusetts Medical School \nTitle: Aneuploidy disrupts cellular physiology and metabolism \nAbstract: An abnormal number of chromosomes or aneuploidy accounts for most spontaneous abortions as missegregation of a single chromosome during development is often lethal. Humans with trisomies for chromosomes 13 or 18\, which cause Patau and Edwards syndromes\, respectively\, are born with severe developmental defects and die soon after birth. Only individuals with trisomy 21\, which causes Down syndrome\, can live to adulthood but show cognitive disabilities\, increased risk for leukemias\, autoimmune disorders\, and clinical symptoms associated with premature aging. Notably\, the incidence of aneuploidy increases with age in both somatic and germline tissues in apparently healthy individuals. The mechanisms by which aneuploidy affects cellular function to cause Down syndrome or promote aging are not well understood. Our studies revealed that aneuploidy disrupts the integrity and morphology of the nuclear membrane. Because mutations that affect nuclear morphology cause premature aging\, we hypothesize that the aneuploidy effects on the nucleus drive phenotypic anomalies associated with premature aging in Down syndrome. In addition\, to characterize aneuploidy-driven phenotypes in human cells\, we performed global transcriptome\, proteome\, and phenotypic analyses of primary fibroblasts from individuals with Patau (trisomy 13)\, Edwards (trisomy 18)\, or Down syndromes. On average\, mRNA and protein levels were increased by 1.5-fold in all trisomies\, with a subset of proteins enriched for subunits of macromolecular complexes showing signs of post-transcriptional regulation. Lastly\, we show that several aneuploidy-associated phenotypes are present in trisomy 21 cells\, including lower viability and increased dependency on serine-driven lipid biosynthesis. Our studies establish a critical role of aneuploidy\, independent of triplicated gene identity\, in driving cellular defects associated with Down syndrome. \nParticipate in this event via Zoom \nDownload event flyer \nFor more information about this seminar\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-eduardo-torres-univ-of-massachusetts-medical-school/
LOCATION:Online
CATEGORIES:Structural Biology
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211105T120000
DTEND;TZID=America/New_York:20211105T130000
DTSTAMP:20260307T230957
CREATED:20211008T164639Z
LAST-MODIFIED:20211014T125716Z
UID:10001096-1636113600-1636117200@asrc.gc.cuny.edu
SUMMARY:Converge to Transform: Interdisciplinary STEM Seminar Series - Robert Wright\, Icahn School of Medicine at Mount Sinai
DESCRIPTION:Speaker: Robert Wright\, MD\, MPH\, Ethel H. Wise Chair of the Department of Environmental Medicine and Public Health and Director of The Institute for Exposomic Research at the Icahn School of Medicine at Mount Sinai \nTitle: Exposomics\, Medicine and Public Health \nRegister for the seminar here: https://asrc.formstack.com/forms/converge_to_transform_series_110521 \nResearchers today simultaneously need to address a growing demand for technological advances and an expanding list of threats to our planet and humanity. Solutions to these challenges will not be realized within siloed areas of research\, but through the kinds of dynamic\, innovative thought produced when researchers work across disciplines. Thus\, the ASRC is hosting a new seminar series for the 2021-22 academic year to highlight outstanding\, high impact\, inspiring interdisciplinary STEM research for the public good. The series will bring together researchers across many disciplines as well as enrich CUNY’s undergraduate\, graduate\, and postdoctoral trainees educational experiences. Speakers in this series will present recent advances in nanomaterials\, nanotechnology\, imaging\, computational biology\, environmental impacts on human health\, epigenetics\, and molecular and cellular causes of cancer and neurodegeneration. \nJoin us on Friday\, November 5 at 12pm for the second speaker in this series: Robert Wright\, MD\, MPH\, Ethel H. Wise Chair of the Department of Environmental Medicine and Public Health\, and Director of The Institute for Exposomic Research at the Icahn School of Medicine at Mount Sinai. He will give a talk titled Exposomics\, Medicine and Public Health. \nA pediatrician\, medical toxicologist\, and environmental epidemiologist\, Dr. Wright studies chemical mixtures\, social stressors as a modifier of chemical toxicity\, and the role of genetics/epigenetics in modifying or mediating chemical toxicity. He is an international advocate for research on exposomics—the measure of all health relevant human exposure throughout the lifespan. In September 2018\, he joined the National Advisory Environmental Health Sciences Council (NAEHSC)\, a Congressionally mandated body that advises the secretary of Health and Human Services\, the director of NIH\, and the director of the National Institute of Environmental Health Sciences (NIEHS) on matters relating to the direction of research\, research support\, training\, and career development supported by the NIEHS.
URL:https://asrc.gc.cuny.edu/event/converge-to-transform-interdisciplinary-stem-seminar-series-robert-wright-icahn-school-of-medicine-at-mount-sinai/
LOCATION:Advanced Science Research Center (ASRC)\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
ATTACH;FMTTYPE=image/png:https://asrc.gc.cuny.edu/wp-content/uploads/media/event/interdisciplinary-stem-seminar-series/CUNY-ASRC-Interdisciplinary-STEM-Seminar-Series.png
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211103T120000
DTEND;TZID=America/New_York:20211103T130000
DTSTAMP:20260307T230957
CREATED:20210901T195944Z
LAST-MODIFIED:20211025T143210Z
UID:10001218-1635940800-1635944400@asrc.gc.cuny.edu
SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Margaret Johnson\, Johns Hopkins University
DESCRIPTION:Speaker: Margaret Johnson\, Assistant Professor\, Dept of Biophysics\, Johns Hopkins University \nTitle: Protein self-assembly at the right time and place \nAbstract: Self-assembly of protein components is ubiquitous across biology\, where these assemblies often must form at specific spatial locations within a cell to do work. In clathrin-mediated endocytosis (CME) and virion formation\, for example\, multiple protein types must localize to the cell’s plasma membrane to ensure proper transport and communication in and out of cells. We develop theory and computational models\, along with collaboration with experimental groups\, to understand and predict how the success and dynamics of multi-protein self-assembly in pathways like CME can be controlled by stoichiometry\, both active and stochastic driving forces\, and membrane localization. We constructed a relatively simple theoretical model that quantifies how dimensional reduction (change in search space from 3D to 2D) can\, on its own\, provide a powerful driving force promoting assembly after membrane localization\, thereby regulating the timing of assembly. We further showed how the membrane can also significantly accelerate assembly kinetics by orders of magnitude\, largely dependent on the rate of arrival and adsorption to the membrane surface. Applying these ideas\, along with new reaction-diffusion software NERDSS developed by our lab\, we showed how nucleation and growth of clathrin proteins into hexagonal lattices on membranes can be sensitively tuned by the so-called adaptor proteins that link clathrin to the surface. Our model was validated to reproduce quantitatively in vitro fluorescence data tracking clathrin localization to membranes\, and predicts regimes of assembly and spontaneous disassembly that are in close agreement with in vivo measurements. An essential role of many membranelocalized assemblies such as these are to remodel the membrane. We have therefore used continuum thin-film models to characterize how such proteins can drive membrane bending using mechanisms such as helix-insertion and scaffolding\, with distinct energetic costs to each. These theoretical and computational approaches are general and can be applied to diverse biological systems\, helping to understand how both hetero- and homo-subunit assemblies can be controlled to function within the nonequilibrium cell. \nDownload the event flyer \nParticipate in this event via Zoom \nFor more information about this seminar\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-margaret-johnson-johns-hopkins-university/
LOCATION:ASRC Auditorium\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Structural Biology
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211101T120000
DTEND;TZID=America/New_York:20211101T130000
DTSTAMP:20260307T230957
CREATED:20210901T193748Z
LAST-MODIFIED:20210901T193748Z
UID:10001213-1635768000-1635771600@asrc.gc.cuny.edu
SUMMARY:Environmental Sciences Initiative AWAKES: Brian Giebel\, CUNY ASRC
DESCRIPTION:Speaker: Brian Giebel\, Ph.D.\, Director\, Advanced Laboratory for Chemical and Isotopic Signatures\, Research Asst. Professor\, CUNY Advanced Science Research Center at The Graduate Center \nUpdates from the ASRC Environmental Sciences Initiative Research Groups 
URL:https://asrc.gc.cuny.edu/event/environmental-sciences-initiative-awakes-brian-giebel-cuny-asrc/
LOCATION:ASRC 5th Floor Data Visualization Room\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Environmental Sciences
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211029T140000
DTEND;TZID=America/New_York:20211029T150000
DTSTAMP:20260307T230957
CREATED:20210811T200239Z
LAST-MODIFIED:20211019T133214Z
UID:10001201-1635516000-1635519600@asrc.gc.cuny.edu
SUMMARY:Science Careers Beyond the Lab: A Conversation With AAAS CEO Sudip Parikh
DESCRIPTION:This event is part of the Communicating Your Science series. \nThis series features presentations by The Graduate Center’s science librarian and communications staff\, journal editors\, and reporters. The goal of this series is to enhance the professional development and science communication skills of CUNY STEM faculty\, postdocs\, and students. Learn more » \n\na special session with AAAS CEO Sudip Parikh and Graduate Center\, CUNY Dean for the Sciences Joshua Brumberg\, who will discuss how a science Ph.D. can lead to careers beyond the lab\, especially in areas such as scientific journals and advocacy work aimed at shaping science policy\, improving STEM education\, diversifying the field and build bridges between researchers and the public. They will cover: \n\nParikh’s path to leading a scientific society\nThe role of AAAS as an advocacy organization and journal publisher\nAAAS student opportunities\n\nThere will be time for Q&A. \nRegister online now to participate » \nFor more information\, contact Shawn Rhea at srhea@gc.cuny.edu.
URL:https://asrc.gc.cuny.edu/event/science-careers-beyond-the-lab/
LOCATION:Online
CATEGORIES:Environmental Sciences,Nanoscience,Neuroscience,Photonics,Structural Biology
ATTACH;FMTTYPE=image/jpeg:https://asrc.gc.cuny.edu/wp-content/uploads/media/events/communicating-your-science-series/Graduate-Center-Science-Academy-Main-Banner_v2.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211027T120000
DTEND;TZID=America/New_York:20211027T130000
DTSTAMP:20260307T230957
CREATED:20210901T195704Z
LAST-MODIFIED:20210901T195704Z
UID:10001217-1635336000-1635339600@asrc.gc.cuny.edu
SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Nozomi Ando\, Cornell University
DESCRIPTION:Speaker: Nozomi Ando\, Associate Professor\, Dept of Chemistry & Chemical Biology\, Cornell University \nTitle: Cornell University \nAbstract: TBD \nFor more information about this seminar and about joining in online\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-nozomi-ando-cornell-university/
LOCATION:Online
CATEGORIES:Structural Biology
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211020T120000
DTEND;TZID=America/New_York:20211020T130000
DTSTAMP:20260307T230957
CREATED:20210901T195346Z
LAST-MODIFIED:20211008T203607Z
UID:10001216-1634731200-1634734800@asrc.gc.cuny.edu
SUMMARY:Seminar in Biochemistry\, Biophysics & Biodesign: Kathryn Wellen\, Univ of Pennsylvania
DESCRIPTION:Speaker: Kathryn Wellen\, Associate Professor\, Dept of Cancer Biology\, Univ of Pennsylvania \nTitle: Metabolic compartmentalization and adaptations in cancer \nAbstract: Cells continually monitor nutrient availability to adapt to their environment and to inform decisions about survival\, proliferation\, and performance of different functions. Accordingly\, many metabolites play crucial roles as signaling molecules\, in addition to their functions in energy production and biosynthesis. In this presentation\, I will discuss two projects. In the first\, I will discuss the application of new methods to assess metabolism in subcellular compartments such as the nucleus to glean new insights into mechanisms of crosstalk between metabolism and the epigenome. In the second\, I will discuss evidence for engagement of a hexosamine salvage mechanism that cancer cells employ in the face of nutrient deprivation in the tumor microenvironment. \nParticipate via zoom \nDownload event flyer \nFor more information about this seminar and about joining in online\, please contact Hyacinth Camillieri at hcamillieri@gc.cuny.edu
URL:https://asrc.gc.cuny.edu/event/seminar-in-biochemistry-biophysics-biodesign-kathryn-wellen-univ-of-pennsylvania/
LOCATION:Online
CATEGORIES:Structural Biology
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211018T120000
DTEND;TZID=America/New_York:20211018T130000
DTSTAMP:20260307T230957
CREATED:20210901T193404Z
LAST-MODIFIED:20210901T193428Z
UID:10001212-1634558400-1634562000@asrc.gc.cuny.edu
SUMMARY:Environmental Sciences Initiative AWAKES: Charles J. Vörösmarty\, CUNY ASRC & CCNY
DESCRIPTION:Speaker: Charles J. Vörösmarty\, Ph.D.\, Director\, Environmental Sciences Initiative\, CUNY Advanced Science Research Center at The Graduate Center\, Professor\, Dept. of Civil Engineering\, The City College of New York \nUpdates from the ASRC Environmental Sciences Initiative Research Groups 
URL:https://asrc.gc.cuny.edu/event/environmental-sciences-initiative-awakes-charles-j-vorosmarty-cuny-asrc-ccny/
LOCATION:ASRC 5th Floor Data Visualization Room\, 85 St. Nicholas Terrace\, New York\, NY\, 10031\, United States
CATEGORIES:Environmental Sciences
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211014T120000
DTEND;TZID=America/New_York:20211014T130000
DTSTAMP:20260307T230957
CREATED:20210930T150910Z
LAST-MODIFIED:20210930T150910Z
UID:10001094-1634212800-1634216400@asrc.gc.cuny.edu
SUMMARY:CUNY Academy for the Humanities and Sciences: Nir London\, Weizmann Institute
DESCRIPTION:To receive the Zoom link\, please send your name and affiliation to mphilipp@gc.cuny.edu. \nSpeaker: Nir London\, Ph.D.\, The Alan and Laraine Fischer Career Development Chair\, Department of Organic Chemistry\, Weizmann Institute of Science \nTitle: Crowdsourcing a Cure for COVID-19 \nAbstract: COVID-19\, caused by SARS-CoV-2\, lacks effective therapeutics. Additionally\, no antiviral drugs or vaccines were developed against the closely related coronavirus\, SARS-CoV-1 or MERS-CoV\, despite previous zoonotic outbreaks. To identify starting points for such therapeutics\, we performed a large-scale screen of electrophile and non-covalent fragments through a combined mass spectrometry and X-ray approach against the SARS-CoV-2 main protease. The results with more than 71 co-crystal structures that span the entire active site\, were released to the public and we implemented a crowd-sourcing platform to solicit next generation design ideas. Thousands of suggestions were submitted\, of which we made and tested >1\,500\, through a global consortium including academic labs\, chemical vendors\, pharma advisors and more. This effort resulted in <100nM inhibitors with crystallographic confirmation and activity in live virus assays. Crowd computing (Folding@Home) was harnessed for compound optimization; AI (via PostEra) for prioritization and retrosynthesis. This is still an on-going live project that can benefit from the input of medicinal chemists world-wide. We hope this initiative can serve as a template for an alternative drug discovery pipeline for areas that are unappealing to traditional pharma such as pandemic preparedness and antibiotic development. 
URL:https://asrc.gc.cuny.edu/event/cuny-academy-for-the-humanities-and-sciences-nir-london-weizmann-institute/
LOCATION:Online
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END:VCALENDAR